Abstract：
Olive family (Oleaceae) contains several species among which Olea europaea L. is mostly used for production of olive oils. Various parts of olive tree are rich source of diverse bioactive compounds such as Apigenin, elenolic acid, Hydroxytyrosol, Ligstroside, Oleoside, Oleuropein, Oleuropein aglycone, Tyrosol, etc. Among these, oleuropein, a secoiridoid is predominantly found in olive leaves and young olive fruits of different species of Oleaceae family. Scientists have adopted numerous extraction methods (conventional & latest) to increase the yield of oleuropein. Among these techniques, maceration, soxhlet, microwave-assisted, ultrasonication, and supercritical fluid methods are most commonly employed for extraction of oleuropein. Evidently, this review emphasizes on various in-vitro and in-vivo studies focusing on nutraceutical properties of oleuropein. Available literature highlights the pharmaceutical potential of oleuropein against various diseases such as obesity, diabetes, cardiovascular complications, neurodegenerative diseases, cancer, inflammation, microbial infections, and oxidation. This review will benefit the scientific community as it narrates comprehensive literature regarding absorption, metabolism, bioavailability, extraction techniques, and nutraceutical perspectives associated with oleuropein.
摘要：
橄榄科（Oleaceae）包含几种物种，其中OleaeuropaeaL.主要用于生产橄榄油。橄榄树的各个部分都是丰富的多种生物活性化合物的来源，如芹菜素，烯醇酸,羟基酪醇，Ligstroside,Oleoside,橄榄苦苷,橄榄苦苷苷配基,Tyrosol,等。其中,橄榄苦苷,主要存在于油豆科不同物种的橄榄叶和年轻的橄榄果实中。科学家已经采用了许多提取方法（常规和最新的）来提高橄榄苦苷的产量。在这些技术中,浸渍,Soxhlet,微波辅助，超声处理,和超临界流体方法最常用于提取橄榄苦苷。显然,这篇综述强调了各种体外和体内研究，重点关注橄榄苦苷的营养特性。现有文献强调了橄榄苦苷对各种疾病如肥胖的药物潜力，糖尿病,心血管并发症,神经退行性疾病，癌症,炎症,微生物感染,和氧化。这篇评论将使科学界受益，因为它讲述了有关吸收的全面文献，新陈代谢，生物利用度，提取技术，以及与橄榄苦苷相关的营养保健观点。
