Mesh : Female Humans Aged Lymphoma, B-Cell, Marginal Zone / complications diagnosis surgery Colonoscopy Diagnosis, Differential Gastrointestinal Hemorrhage / etiology surgery diagnosis Peptic Ulcer / diagnosis

来  源:   DOI:10.1097/MD.0000000000033869   PDF(Pubmed)

Abstract:
BACKGROUND: Colonic extranodal mucosa-associated lymphoid tissue lymphoma as a cause of hematochezia is rare. Here, we report a case of colonic extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue (MALToma) with presentation of freshy bloody stool and successfully treated by endoscopic mucosal resection.
METHODS: This case was a 69-year-old woman with history of hypertension, reflux esophagitis, and peptic ulcer. She had several episodes of hematochezia and thus sought medical attention at the outpatient clinic.
METHODS: Colonoscopy revealed a 12-mm semipedunculated lesion in the ascending colon. Histopathological examination and immunochemistry were compatible with colonic extranodal mucosa-associated lymphoid tissue lymphoma.
METHODS: Endoscopic mucosal resection was done for tumor removal and hemoclipping was done to achieve hemostasis.
RESULTS: The patient remained well without recurrence during 3 years of outpatient follow-up.
CONCLUSIONS: Colonic MALToma is a rare disease, and could present as hematochezia. En bloc endoscopic resection could achieve long-term remission. The prognosis of colonic MALToma is excellent with its indolent characteristics.
摘要:
背景:结肠结外粘膜相关淋巴组织淋巴瘤作为便血的原因很少见。这里,我们报道了一例结肠结外边缘区粘膜相关淋巴组织淋巴瘤(MALToma),伴有新鲜血便,经内镜粘膜切除术成功治疗.
方法:该病例是一名69岁女性,有高血压病史,反流性食管炎,和消化性溃疡.她有几次便血发作,因此在门诊寻求医疗护理。
方法:结肠镜检查显示升结肠有一个12毫米的半带蒂病变。组织病理学检查和免疫化学与结肠结外粘膜相关淋巴组织淋巴瘤兼容。
方法:进行内镜下黏膜切除术切除肿瘤,并进行止血。
结果:患者在3年的门诊随访期间没有复发。
结论:结肠MALToma是一种罕见的疾病,并可能表现为便血。整块内镜切除可获得长期缓解。结肠MALToma的预后良好,具有惰性特征。
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