{Reference Type}: Review
{Title}: A rare cause of hematochezia: colonic extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue (MALToma): A case report and literature review.
{Author}: Lu CH;Kao WY;Chang CC;Kan YA;
{Journal}: Medicine (Baltimore)
{Volume}: 102
{Issue}: 21
{Year}: 2023 May 26
{Factor}: 1.817
{DOI}: 10.1097/MD.0000000000033869
{Abstract}: <B>BACKGROUND: </B>Colonic extranodal mucosa-associated lymphoid tissue lymphoma as a cause of hematochezia is rare. Here, we report a case of colonic extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue (MALToma) with presentation of freshy bloody stool and successfully treated by endoscopic mucosal resection.<BR><B>METHODS: </B>This case was a 69-year-old woman with history of hypertension, reflux esophagitis, and peptic ulcer. She had several episodes of hematochezia and thus sought medical attention at the outpatient clinic.<BR><B>METHODS: </B>Colonoscopy revealed a 12-mm semipedunculated lesion in the ascending colon. Histopathological examination and immunochemistry were compatible with colonic extranodal mucosa-associated lymphoid tissue lymphoma.<BR><B>METHODS: </B>Endoscopic mucosal resection was done for tumor removal and hemoclipping was done to achieve hemostasis.<BR><B>RESULTS: </B>The patient remained well without recurrence during 3 years of outpatient follow-up.<BR><B>CONCLUSIONS: </B>Colonic MALToma is a rare disease, and could present as hematochezia. En bloc endoscopic resection could achieve long-term remission. The prognosis of colonic MALToma is excellent with its indolent characteristics.