PDF(Pubmed)
Abstract：
BACKGROUND: Bacterial meningitis caused by non-typhoid Salmonella can be a fatal condition which is more common in low and middle-income countries.
METHODS: We report the case of a Salmonella meningitis in a Belgian six-month old male infant. The first clinical examination was reassuring, but after a few hours, his general state deteriorated. A blood test and a lumbar puncture were therefore performed. The cerebrospinal fluid analysis was compatible with a bacterial meningitis which was later identified by the NRC (National Reference Center) as Salmonella enterica serovar Durban.
CONCLUSIONS: In this paper, we present the clinical presentation, genomic typing, and probable sources of infection for an unusually rare serovar of Salmonella. Through an extended genomic analysis, we established its relationship to historical cases with links to Guinea.
METHODS: We report the case of a Salmonella meningitis in a Belgian six-month old male infant. The first clinical examination was reassuring, but after a few hours, his general state deteriorated. A blood test and a lumbar puncture were therefore performed. The cerebrospinal fluid analysis was compatible with a bacterial meningitis which was later identified by the NRC (National Reference Center) as Salmonella enterica serovar Durban.
CONCLUSIONS: In this paper, we present the clinical presentation, genomic typing, and probable sources of infection for an unusually rare serovar of Salmonella. Through an extended genomic analysis, we established its relationship to historical cases with links to Guinea.
摘要：
背景：由非伤寒沙门氏菌引起的细菌性脑膜炎可能是一种致命疾病，在低收入和中等收入国家更为常见。
方法：我们报告一例比利时6个月大男婴感染沙门氏菌脑膜炎的病例。第一次临床检查让人放心，但几个小时后,他的总体状况恶化了。因此进行血液测试和腰椎穿刺。脑脊液分析与细菌性脑膜炎兼容，细菌性脑膜炎后来被NRC（国家参考中心）鉴定为肠道沙门氏菌。
结论：在本文中，我们提出了临床表现，基因组分型，以及一种罕见的沙门氏菌血清变型的可能感染源。通过扩展的基因组分析，我们建立了它与历史案例的关系，与几内亚有联系。
方法：我们报告一例比利时6个月大男婴感染沙门氏菌脑膜炎的病例。第一次临床检查让人放心，但几个小时后,他的总体状况恶化了。因此进行血液测试和腰椎穿刺。脑脊液分析与细菌性脑膜炎兼容，细菌性脑膜炎后来被NRC（国家参考中心）鉴定为肠道沙门氏菌。
结论：在本文中，我们提出了临床表现，基因组分型，以及一种罕见的沙门氏菌血清变型的可能感染源。通过扩展的基因组分析，我们建立了它与历史案例的关系，与几内亚有联系。
