关键词: Multiple sclerosis neuropathic pain pain quality of life.

来  源:   DOI:10.5606/tftrd.2022.10524   PDF(Pubmed)

Abstract:
UNASSIGNED: This study aims to identify the factors associated with pain and neuropathic pain (NP) in patients with multiple sclerosis (MS) and to determine the relationship between pain and NP with disability, functionality, activities of daily living, fatigue, mood, and quality of life (QoL).
UNASSIGNED: Between July 2017 and October 2017, a total of 100 adult patients with MS (18 males, 82 females; mean age: 35.3±9.9 years; range, 19 to 71 years) were included. All patients were evaluated in terms of pain and NP. Patients with and without pain, and patients with and without NP were compared in terms of sociodemographic characteristics, disease data, disability, functionality, daily living activities, fatigue severity, mood, and QoL using various scales.
UNASSIGNED: A total of 62% of the patients had pain. Pain was found to be associated with low education level (p=0.014), increased fatigue (p<0.001), depressive mood (p<0.001) and lower QoL (p<0.001). A total of 29.03% of patients with pain had NP. Patients with NP had a greater pain intensity (p<0.001) and fatigue (p=0.002) and lower QoL (p=0.011). The number of patients who received the correct treatment for their symptoms was low.
UNASSIGNED: Pain and NP should be better investigated and treated by physicians, as these symptoms are common in MS and adversely affect the QoL and social relations of affected patients and reduce their productivity.
摘要:
本研究旨在确定多发性硬化症(MS)患者与疼痛和神经性疼痛(NP)相关的因素,并确定疼痛与NP与残疾之间的关系,功能,日常生活活动,疲劳,心情,和生活质量(QoL)。
在2017年7月至2017年10月之间,共有100名成年MS患者(18名男性,82名女性;平均年龄:35.3±9.9岁;范围,包括19至71年)。对所有患者进行疼痛和NP方面的评估。有和没有疼痛的患者,和有和没有NP的患者在社会人口统计学特征方面进行比较,疾病数据,残疾,功能,日常生活活动,疲劳严重程度,心情,和QoL使用各种量表。
总共62%的患者有疼痛。发现疼痛与低教育水平有关(p=0.014),疲劳增加(p<0.001),抑郁情绪(p<0.001)和较低的QoL(p<0.001)。共有29.03%的疼痛患者患有NP。NP患者的疼痛强度(p<0.001)和疲劳(p=0.002)和QoL较低(p=0.011)。接受正确治疗的患者数量很少。
医生应更好地调查和治疗疼痛和NP,因为这些症状在MS中很常见,会对患者的QoL和社会关系产生不利影响,并降低其生产力。
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