Abstract:
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has led to the emergence of a wide range of complications, including those affecting the cardiovascular system. In this case series, we present four patients who developed complete atrioventricular block, a serious and potentially life-threatening heart rhythm disorder, during the course of their coronavirus disease 2019 (COVID-19) illness. The mechanisms by which SARS-CoV-2 may lead to arrhythmias are not fully understood but may involve direct infection and damage to heart tissue, as well as inflammation and cytokine storms. The extent and duration of complete heart block varied among these cases, highlighting the need for further research to understand the spectrum of disease and to improve mortality and morbidity in future waves of SARS-CoV-2 infections. We hope that this case series will draw attention to this serious complication of COVID-19 and inspire further research to improve management and outcomes for affected patients.
摘要:
严重急性呼吸系统综合症冠状病毒2(SARS-CoV-2)大流行导致各种并发症的出现,包括那些影响心血管系统的。在这个系列中,我们介绍了4例发生完全性房室传导阻滞的患者,严重的可能危及生命的心律紊乱,在他们2019年冠状病毒病(COVID-19)疾病的过程中。SARS-CoV-2可能导致心律失常的机制尚未完全了解,但可能涉及对心脏组织的直接感染和损害。以及炎症和细胞因子风暴。在这些病例中,完全性心脏传导阻滞的程度和持续时间各不相同,强调需要进一步研究,以了解疾病谱,并在未来的SARS-CoV-2感染浪潮中提高死亡率和发病率。我们希望这个病例系列能够引起人们对COVID-19这一严重并发症的关注,并激发进一步的研究,以改善受影响患者的管理和预后。