Abstract：
Mitochondria perform a myriad of essential functions that ensure organismal homeostasis, including maintaining bioenergetic capacity, sensing and signalling the presence of pathogenic threats, and determining cell fate. Their function is highly dependent on mitochondrial quality control and the appropriate regulation of mitochondrial size, shape, and distribution during an entire lifetime, as well as their inheritance across generations. The roundworm Caenorhabditis elegans has emerged as an ideal model organism through which to study mitochondria. The remarkable conservation of mitochondrial biology has allowed C. elegans researchers to investigate complex processes that are challenging to study in higher organisms. In this review, we explore the key recent contributions of C. elegans to mitochondrial biology through the lens of mitochondrial dynamics, organellar removal, and mitochondrial inheritance, as well as their involvement in immune responses, various types of stress, and transgenerational signalling.
摘要：
线粒体执行无数的基本功能，确保有机体的稳态，包括保持生物能量能力，感知并发出致病威胁的信号，并决定细胞命运。它们的功能高度依赖于线粒体质量控制和线粒体大小的适当调节，形状,在整个生命周期中进行分配，以及他们几代人的遗产。线虫线虫已成为研究线粒体的理想模型生物。线粒体生物学的显着保守性使C.elegans研究人员能够研究复杂的过程，这些过程在高等生物中具有挑战性。在这次审查中,我们通过线粒体动力学的透镜探索秀丽隐杆线虫对线粒体生物学的关键近期贡献，细胞器去除，和线粒体遗传，以及它们参与免疫反应，各种类型的压力，和跨代信号。
