PDF(Pubmed)
Abstract：
Cerebral perfusion is maintained at a consistent value irrespective of changes in systemic blood pressure or disease-induced changes in general physical condition. This regulatory mechanism is effective despite postural changes, working even during changes in posture, such as those from sitting to standing or from the head-down to the head-up position. However, no study has addressed changes in perfusion separately in the left and right cerebral hemispheres, and there has been no specific investigation of the effect of the lateral decubitus position on perfusion in each hemisphere. Surgery, particularly respiratory surgery, is often performed with the patient in the lateral decubitus position, and since intraoperative anesthesia may also have an effect, it is important to ascertain the effect of the lateral decubitus position on perfusion in the left and right cerebral hemispheres in the absence of anesthesia. The effects of the lateral decubitus position on heart rate, blood pressure, and hemodynamic in the left and right cerebral hemispheres assessed by regional saturation of oxygen measured by near-infrared spectroscopy were investigated in healthy adult volunteers. Although the lateral decubitus position causes systemic circulatory changes, it may not cause any difference in hemodynamic between the left and right cerebral hemispheres.
摘要：
无论全身血压的变化或一般身体状况的疾病引起的变化，脑灌注都保持在一致的值。尽管姿势改变，这种调节机制仍然有效，即使在姿势改变时也能工作，例如从坐到站或从低头到抬头的位置。然而,没有研究解决左右大脑半球灌注的变化，并且没有关于侧卧位对每个半球灌注的影响的具体研究。手术,尤其是呼吸外科,通常在患者处于侧卧位的情况下进行，由于术中麻醉也可能有影响，在没有麻醉的情况下，确定侧卧位对左右大脑半球灌注的影响很重要。侧卧位对心率的影响,血压,在健康的成年志愿者中研究了通过近红外光谱测量的区域氧饱和度评估的左右大脑半球的血液动力学。尽管侧卧位会引起全身循环变化，它可能不会引起左右大脑半球之间的血液动力学的任何差异。
