We collected the clinical and radiological data of children aged 1 month-15 years who had ischemic stroke with definite arteriopathy following a recent febrile infection. Repeated neuroimaging was done over the next year to ascertain recurrent strokes and the progression and resolution of arteriopathies.
The anterior circulation was more frequently affected (83.33%), predominantly involving the middle cerebral artery (41.67%), resolving in 20.84% of cases and progressing in 33.33% of cases. Lesions were commonly unilateral (54.17%) and stenotic (75%), resulting predominantly in cortical infarcts (45.83%), with hemiparesis being the most common neurodeficiency. Apart from tubercular meningitis patients, others had a good functional outcome.
Lower age, minor infections, and unilateral arteriopathies had a significantly higher chance of resolution. Postviral arteriopathies had a significantly lower chance of progression compared with those following bacterial infections. Progressive and bilateral arteriopathies were significantly associated with worse outcomes and recurrent strokes.
方法:我们收集了1个月-15岁儿童的临床和放射学数据,这些儿童在最近的高热感染后患有明确的动脉病变。在接下来的一年中进行了重复的神经成像,以确定复发性中风以及动脉病变的进展和消退。
结果:前循环受影响更频繁(83.33%),主要累及大脑中动脉(41.67%),20.84%的病例得到解决,33.33%的病例正在进展。病变通常为单侧(54.17%)和狭窄(75%),主要导致皮质梗死(45.83%),偏瘫是最常见的神经缺陷。除了结核性脑膜炎患者,其他人有一个良好的功能结果。
结论:年龄较低,轻微感染,单侧动脉病变的消退机会明显更高。与细菌感染后相比,病毒后动脉病变的进展机会显着降低。进展性和双侧动脉病变与不良预后和复发性中风显着相关。