Abstract：
Major and minor pediatric infections may cause intracranial arteriopathies, the long-term outcome of which we investigated and identified the factors influencing the progression/resolution of arteriopathies.
We collected the clinical and radiological data of children aged 1 month-15 years who had ischemic stroke with definite arteriopathy following a recent febrile infection. Repeated neuroimaging was done over the next year to ascertain recurrent strokes and the progression and resolution of arteriopathies.
The anterior circulation was more frequently affected (83.33%), predominantly involving the middle cerebral artery (41.67%), resolving in 20.84% of cases and progressing in 33.33% of cases. Lesions were commonly unilateral (54.17%) and stenotic (75%), resulting predominantly in cortical infarcts (45.83%), with hemiparesis being the most common neurodeficiency. Apart from tubercular meningitis patients, others had a good functional outcome.
Lower age, minor infections, and unilateral arteriopathies had a significantly higher chance of resolution. Postviral arteriopathies had a significantly lower chance of progression compared with those following bacterial infections. Progressive and bilateral arteriopathies were significantly associated with worse outcomes and recurrent strokes.
We collected the clinical and radiological data of children aged 1 month-15 years who had ischemic stroke with definite arteriopathy following a recent febrile infection. Repeated neuroimaging was done over the next year to ascertain recurrent strokes and the progression and resolution of arteriopathies.
The anterior circulation was more frequently affected (83.33%), predominantly involving the middle cerebral artery (41.67%), resolving in 20.84% of cases and progressing in 33.33% of cases. Lesions were commonly unilateral (54.17%) and stenotic (75%), resulting predominantly in cortical infarcts (45.83%), with hemiparesis being the most common neurodeficiency. Apart from tubercular meningitis patients, others had a good functional outcome.
Lower age, minor infections, and unilateral arteriopathies had a significantly higher chance of resolution. Postviral arteriopathies had a significantly lower chance of progression compared with those following bacterial infections. Progressive and bilateral arteriopathies were significantly associated with worse outcomes and recurrent strokes.
摘要：
背景：主要和次要的儿科感染可能导致颅内动脉病变，我们调查并确定了影响动脉病变进展/消退的因素。
方法：我们收集了1个月-15岁儿童的临床和放射学数据，这些儿童在最近的高热感染后患有明确的动脉病变。在接下来的一年中进行了重复的神经成像，以确定复发性中风以及动脉病变的进展和消退。
结果：前循环受影响更频繁（83.33%），主要累及大脑中动脉（41.67%），20.84%的病例得到解决，33.33%的病例正在进展。病变通常为单侧（54.17％）和狭窄（75％），主要导致皮质梗死（45.83%），偏瘫是最常见的神经缺陷。除了结核性脑膜炎患者,其他人有一个良好的功能结果。
结论：年龄较低，轻微感染,单侧动脉病变的消退机会明显更高。与细菌感染后相比，病毒后动脉病变的进展机会显着降低。进展性和双侧动脉病变与不良预后和复发性中风显着相关。
方法：我们收集了1个月-15岁儿童的临床和放射学数据，这些儿童在最近的高热感染后患有明确的动脉病变。在接下来的一年中进行了重复的神经成像，以确定复发性中风以及动脉病变的进展和消退。
结果：前循环受影响更频繁（83.33%），主要累及大脑中动脉（41.67%），20.84%的病例得到解决，33.33%的病例正在进展。病变通常为单侧（54.17％）和狭窄（75％），主要导致皮质梗死（45.83%），偏瘫是最常见的神经缺陷。除了结核性脑膜炎患者,其他人有一个良好的功能结果。
结论：年龄较低，轻微感染,单侧动脉病变的消退机会明显更高。与细菌感染后相比，病毒后动脉病变的进展机会显着降低。进展性和双侧动脉病变与不良预后和复发性中风显着相关。
