Abstract：
People with mental defects are more likely to get the infection due to their low levels of health care and personal hygiene. The current study aimed to determine the seroprevalence of Toxoplasma infection among individuals with intellectual disabilities in Hormozgan province, southern Iran.
The study population was 117 individuals with intellectual disabilities. Venous blood (3 mL) was taken from each subject. A commercial ELISA kit was used to determine anti-Toxoplasma IgG antibodies.
Of 117 recruited subjects, 55 (47.0%) were men and 62 (53.0%) were women. The mean age of participants was 27.6 (±12.31) years. Out of 117 studied subjects, 76 had severe and 41 had profound intellectual disabilities. Anti-Toxoplasma IgG antibodies were detected in the sera of 35 out of 117 (29.9%) individuals. Seropositivity to toxoplasmosis was significantly higher in severe than in individuals with profound intellectual disabilities (P < 0.05). There was no statistically significant association between Toxoplasma infection and age, sex and duration of residency in the rehabilitation centre.
The findings of this study indicate that the prevalence of Toxoplasma in people with intellectual disabilities is not much different from other groups of the community.
The study population was 117 individuals with intellectual disabilities. Venous blood (3 mL) was taken from each subject. A commercial ELISA kit was used to determine anti-Toxoplasma IgG antibodies.
Of 117 recruited subjects, 55 (47.0%) were men and 62 (53.0%) were women. The mean age of participants was 27.6 (±12.31) years. Out of 117 studied subjects, 76 had severe and 41 had profound intellectual disabilities. Anti-Toxoplasma IgG antibodies were detected in the sera of 35 out of 117 (29.9%) individuals. Seropositivity to toxoplasmosis was significantly higher in severe than in individuals with profound intellectual disabilities (P < 0.05). There was no statistically significant association between Toxoplasma infection and age, sex and duration of residency in the rehabilitation centre.
The findings of this study indicate that the prevalence of Toxoplasma in people with intellectual disabilities is not much different from other groups of the community.
摘要：
背景：患有精神缺陷的人更容易感染，因为他们的医疗保健和个人卫生水平较低。本研究旨在确定霍尔木兹甘省智障人士弓形虫感染的血清阳性率，伊朗南部。
方法：研究人群为117名智障人士。从每个受试者取静脉血(3mL)。商业ELISA试剂盒用于测定抗弓形虫IgG抗体。
结果：在117名招募的受试者中，55（47.0%）为男性，62（53.0%）为女性。参与者的平均年龄为27.6(±12.31)岁。在117个研究对象中，76人患有严重的智力障碍，41人患有严重的智力障碍。在117名个体中的35名(29.9%)的血清中检测到抗弓形虫IgG抗体。重度智力障碍患者对弓形虫病的血清阳性率明显高于重度智力障碍患者（P<0.05）。弓形虫感染与年龄之间没有统计学上的显着关联，在康复中心居住的性别和持续时间。
结论：这项研究的结果表明，智障人群中弓形虫的患病率与社区其他人群没有太大差异。
方法：研究人群为117名智障人士。从每个受试者取静脉血(3mL)。商业ELISA试剂盒用于测定抗弓形虫IgG抗体。
结果：在117名招募的受试者中，55（47.0%）为男性，62（53.0%）为女性。参与者的平均年龄为27.6(±12.31)岁。在117个研究对象中，76人患有严重的智力障碍，41人患有严重的智力障碍。在117名个体中的35名(29.9%)的血清中检测到抗弓形虫IgG抗体。重度智力障碍患者对弓形虫病的血清阳性率明显高于重度智力障碍患者（P<0.05）。弓形虫感染与年龄之间没有统计学上的显着关联，在康复中心居住的性别和持续时间。
结论：这项研究的结果表明，智障人群中弓形虫的患病率与社区其他人群没有太大差异。
