Abstract：
CD151 is a transmembrane protein implicated in tumor progression and has been shown to regulate various cellular and molecular mechanisms contributing to malignancy. More recently, the role of CD151 in the tumor immune microenvironment (TIME) has gained attention as a potential target for cancer therapy. This review aims to explore the role of CD151 in the TIME, focusing on the therapeutic and clinical perspectives. The role of CD151 in regulating the interactions between tumor cells and the immune system will be discussed, along with the current understanding of the molecular mechanisms underlying these interactions. The current state of the development of CD151-targeted therapies and the potential clinical applications of these therapies will also be reviewed. This review provides an overview of the current knowledge on the role of CD151 in the TIME and highlights the potential of CD151 as a therapeutic target for cancer treatment.
摘要：
CD151是参与肿瘤进展的跨膜蛋白,并且已经显示调节促成恶性肿瘤的各种细胞和分子机制。最近,CD151在肿瘤免疫微环境(TIME)中的作用作为癌症治疗的潜在靶点而备受关注.这篇综述旨在探讨CD151在时代，专注于治疗和临床观点。将讨论CD151在调节肿瘤细胞与免疫系统之间的相互作用中的作用，以及目前对这些相互作用的分子机制的理解。还将回顾CD151靶向疗法的发展现状以及这些疗法的潜在临床应用。这篇综述概述了CD151在TIME中的作用，并强调了CD151作为癌症治疗靶点的潜力。
