Abstract：
The introduction of long-acting injectable buprenorphine preparations for opioid use disorder has been widely heralded as a breakthrough treatment, with several studies indicating positive results when using these medications. In many locations, nurse practitioners prescribe, administer, and monitor long-acting injectable preparations. The objective of this paper is to explore whether a reduction in dispensed needles and syringes is attributable to increased nurse practitioner prescribing of LAIB. We used a retrospective audit of needles dispensed through the health service needle and syringe program vending machine, and individuals treated with long-acting injectable buprenorphine by the nurse practitioner led model. In addition, we examined potential factors that may influence changes in the number of needles dispensed. Linear regression found that each individual with opioid dependence treated with long-acting injectable buprenorphine was associated with 90 fewer needles dispensed each month (p < 0.001). The nurse practitioner led model of care for individuals with opioid dependence appears to have influenced the number of needles dispensed at the needle and syringe program. Although all confounding factors could not be discounted entirely, such as substance availability, affordability, and individuals obtaining injecting equipment elsewhere, our research indicates that a nurse practitioner led model of treating individuals with opioid use disorder influenced needle and syringe dispensing in the study setting.
摘要：
长效丁丙诺啡注射剂用于阿片类药物使用障碍已被广泛预示为突破性治疗，几项研究表明，当使用这些药物时，结果是积极的。在许多地方,执业护士开处方，administrate,并监测长效注射制剂。本文的目的是探讨分配的针头和注射器的减少是否归因于LAIB处方的增加。我们对通过卫生服务针头和注射器程序自动售货机分配的针头进行了回顾性审核，以及由执业护士领导的模型用长效注射丁丙诺啡治疗的个体。此外,我们研究了可能影响分配针头数量变化的潜在因素.线性回归发现，使用长效可注射丁丙诺啡治疗的阿片类药物依赖患者每个月分配的针头减少90个（p<0.001）。执业护士领导的阿片类药物依赖患者的护理模型似乎影响了针头和注射器计划中分配的针头数量。尽管所有混杂因素都不能完全打折扣，如物质可用性，负担能力，以及在其他地方获得注射设备的个人，我们的研究表明,在研究环境中,一名执业护士领导的阿片类药物使用障碍患者治疗模型影响了针头和注射器的分配.
