PDF(Pubmed)
Abstract：
Vibrio anguillarum is a cause of vibriosis in marine fisheries worldwide, but only one previous study reported human pathogenicity of this species. Here, we report a 70-year-old man from Dalian, a coastal city in northeast China, who experienced a severe infection with V. anguillarum due to a bite on his left hand when handling hairtail, a marine fish. This patient had low immunity because of the long-term use of glucocorticoids due to nephrotic syndrome. Despite treatments consisting of a strong antibiotic, continuous veno-venous hemofiltration, debridement, and fasciotomy, his condition deteriorated and he died of septic shock and multiple organ dysfunction syndrome. His death might be partly due to the delayed amputation of the left forearm, because he seemed to get better for the first several days. This case report emphasizes the possibility of human infection by V. anguillarum, which is likely to be more lethal in immunocompromised individuals.
摘要：
anguillarum弧菌是全球海洋渔业中弧菌病的原因，但之前只有一项研究报道了该物种对人类的致病性。这里,我们报道了一个来自大连的70岁老人,中国东北的一个沿海城市，他在处理带鱼时左手被咬伤，严重感染了anguillarum，海鱼.该患者因肾病综合征长期使用糖皮质激素而免疫力低下。尽管治疗包括强效抗生素，连续静脉-静脉血液滤过,清创术,筋膜切开术,病情恶化，死于感染性休克和多器官功能障碍综合征。他的死亡可能部分是由于左前臂的延迟截肢，因为他似乎在最初的几天里好转了。本病例报告强调了人感染anguillarum的可能性，这在免疫受损的个体中可能更致命。
