Abstract：
Recent years have seen a lot of interest in transition metal carbides/carbonitrides (MXenes), Which is one of newly proliferating two-dimensional (2D) materials.The advantages and applications of synthesizing MXenes-based biosensing systems are interesting. There is an urgent requirement for synthesis of MXenes. Through foliation, physical adsorption, and interface modification,it has been proposed that many biological disorders are related to genetic mutation. Majority of mutations were discovered to be nucleotide mismatches. Consequently, accurate -nucleotide mismatched discrimination is crucial for both diagnosing and treating diseases. To differentiate between such a sensitivealterations in the DNA duplex, several detection methods, particularly Electrochemical-luminescence (ECL) ones, have really been investigated.Mn+1XnTx is common name for MXenes, a novel family of two-dimensional (2D) transition metal carbides, nitrides, and carbonitrides, where T stands for interface termination units (i.e. = O, OH, and/or F). These electronic characteristics of MXenes may be changed between conductive to semiconducting due to abundant organometallic chemistry.Solid-state ECL sensors predicated on MXene would provide the facile nucleotide detection and convenience for usage with minimal training, mobility and possibly minimal cost.This study emphasizes upcoming requirements and possibilities in this area while describing the accomplishments achieved in the usage and employing of MXenes in the research and development of facile biomarkerdetection and their significance in designing electrochemical sensors. Opportunities are addressed for creating 2D MXene materials sensors and devices with incorporated biomolecule sensing. MXenes Carry out this process sensors, address the advantages of using MXenes and their variants as detecting materials for gathering different types of data, and attempt to clarify the design principles and operation of related MXene-based sensors, such as nucleotide detection, Single nucleotide detectors, Cancer theranostics, Biosensing capabilities, Gliotoxin detection, SARS-COV-2 nucleocapsid detection, electrochemical sensors, visual sensors, and humidity sensors. Finally, we examine the major issues and prospects for MXene-based materials used in various sensing applications.
摘要：
近年来，人们对过渡金属碳化物/碳氮化物（MXenes）产生了极大的兴趣，这是一种新扩散的二维(2D)材料。合成基于MXenes的生物传感系统的优点和应用是有趣的。迫切需要合成MXenes。通过落叶，物理吸附，和接口修改，有人提出，许多生物疾病与基因突变有关。发现大多数突变是核苷酸错配。因此,准确的核苷酸错配辨别对于诊断和治疗疾病都是至关重要的。为了区分DNA双链体的这种敏感改变，几种检测方法，特别是电化学发光(ECL)的，真的被调查了。Mn+1XnTx是MXenes的通用名称，一个新颖的二维（2D）过渡金属碳化物家族，氮化物，和碳氮化物，其中T代表接口终端单元(即=O，OH,和/或F）。由于丰富的有机金属化学,MXenes的这些电子特性可以在导电到半导体之间改变。基于MXene的固态ECL传感器将提供简单的核苷酸检测和使用便利，只需最少的培训，移动性和可能的最小成本。这项研究强调了这一领域即将到来的要求和可能性，同时描述了在使用和使用MXenes进行简易生物标志物检测的研究和开发中取得的成就及其在设计电化学传感器中的意义。创造结合生物分子传感的2DMXene材料传感器和设备的机会得到了解决。MXenes执行此过程传感器,解决使用MXenes及其变体作为收集不同类型数据的检测材料的优势，并试图阐明相关的基于MXene的传感器的设计原则和操作，如核苷酸检测，单核苷酸检测器,癌症治疗药，生物传感能力，胶质毒素检测，SARS-COV-2核衣壳检测，电化学传感器，视觉传感器,和湿度传感器。最后,我们研究了用于各种传感应用的MXene基材料的主要问题和前景。
