This is a protocol for a cross-sectional case-control study with 170 KOA patients and 170 age- and gender-matched healthy individuals. Diagnosed patients aged 45 to 70 will be recruited in the KOA group. Participants in the healthy group will be matched with the KOA group based on mean age and gender distribution. Skin temperature of 11 acupoints (ST35, EX-LE5, GB33, GB34, EX-LE2, ST34, ST36, GB39, BL40, SP9, SP10) will be extracted from infrared thermography (IRT) images of the lower limbs. Other measurements will include demographic data (gender, age, ethnicity, education, height, weight, BMI) and disease-related data (numerical rating scale, pain sites, duration of pain, pain descriptors, pain activities).
The results of this study will provide biological evidence for acupoint selection. This study is a precondition for follow-up studies, in which the value of optimized acupoint selection will be verified.
ChiCTR2200058867.
方法:这是一项针对170名KOA患者和170名年龄和性别匹配的健康个体的横断面病例对照研究的方案。将在KOA组中招募45至70岁的诊断患者。健康组的参与者将根据平均年龄和性别分布与KOA组进行匹配。将从下肢的红外热成像(IRT)图像中提取11个穴位(ST35,EX-LE5,GB33,GB34,EX-LE2,ST34,ST36,GB39,BL40,SP9,SP10)的皮肤温度。其他测量将包括人口统计数据(性别,年龄,种族,教育,高度,体重,BMI)和疾病相关数据(数字评定量表,疼痛部位,疼痛的持续时间,疼痛描述,疼痛活动)。
结论:本研究结果将为选穴提供生物学依据。这项研究是后续研究的前提,其中优化选穴的价值将得到验证。
背景:ChiCTR2200058867。