PDF(Pubmed)
Abstract：
Background: Stressful events during a pandemic are a major cause of serious health problems, such as burnout, depression and posttraumatic stress disorder (PTSD) among health care workers (HCWs). During three years, HCWs, on the frontline to fight the COVID-19 pandemic, have been at an increased risk of high levels of stress, anxiety, depression, burnout and PTSD. Regarding potential psychological interventions, Eye Movement Desensitization & Reprocessing (EMDR) is a structured, strongly recommended therapy based on its well-known efficacy in reducing PTSD symptoms and anxiety.Objectives: This study, designed as a trial within a cohort (TwiC), aims to 1) estimate the prevalence of depression, burnout and PTSD in a sample of HCWs after experiencing the COVID-19 emergency (cohort part) and 2) assess the efficacy and acceptability of \'EMDR + usual care\' for HCWs from the cohort who report significant psychological symptoms (trial part).Methods: The study, designed as a TwiC, consists of a prospective cohort study (n = 3000) with an embedded, pragmatic, randomized open-label superiority trial with two groups (n = 900). Participants included in the trial part are HCWs recruited for the cohort with significant symptoms on at least one psychological dimension (depression, burnout, PTSD) at baseline, 3 months or 6 months, determined by using the Patient Health Questionnaire (PHQ-9), Professional Quality of Life (ProQOL) scale, and PTSD Checklist for the DSM-5 (PCL-5). The intervention consists of 12 separate EMDR sessions with a certified therapist. The control group receives usual care. The trial has three primary outcomes: changes in depression, burnout and PTSD scores from randomization to 6 months. All participants are followed up for 12 months.Conclusions: This study provides empirical evidence about the impact of the COVID-19 pandemic and the mental health burden it places on HCWs and assesses the effectiveness of EMDR as a psychological intervention.Trial registration NCT04570202.
Health care workers are at increased risk of stress, anxiety, depression, burnout and PTSD following the COVID-19 pandemic.In this study, the effectiveness of EMDR in reducing depression, burnout and PTSD in health care workers exposed to COVID-19 is investigated.In this study, an original ‘trial within a cohort’ (TwiC) design that consists of a cohort study with an embedded pragmatic randomized trial is used.The study is fully web-based, including online screening, consent and assessments.
Health care workers are at increased risk of stress, anxiety, depression, burnout and PTSD following the COVID-19 pandemic.In this study, the effectiveness of EMDR in reducing depression, burnout and PTSD in health care workers exposed to COVID-19 is investigated.In this study, an original ‘trial within a cohort’ (TwiC) design that consists of a cohort study with an embedded pragmatic randomized trial is used.The study is fully web-based, including online screening, consent and assessments.
摘要：
背景：大流行期间的应激事件是严重健康问题的主要原因，比如倦怠，医护人员(HCWs)中的抑郁和创伤后应激障碍(PTSD)。三年来,HCWs,在抗击COVID-19大流行的前线，承受高压力的风险增加，焦虑,抑郁症,倦怠和创伤后应激障碍。关于潜在的心理干预，眼动脱敏和后处理(EMDR)是一种结构化的，基于其在减轻PTSD症状和焦虑方面的众所周知的功效，强烈推荐治疗。目的:本研究,设计为队列中的试验(TwiC)，旨在1)估计抑郁症的患病率，经历COVID-19紧急情况后的HCW样本中的倦怠和创伤后应激障碍(队列部分)和2)评估报告显著心理症状的队列中的HCW的“EMDR+常规护理”的疗效和可接受性(试验部分)。方法:研究,被设计成Twic，由一项前瞻性队列研究(n=3000)组成，务实,随机开放标签优势试验分为两组(n=900).纳入试验部分的参与者是为队列招募的HCWs，在至少一个心理维度上有显著症状(抑郁，倦怠,PTSD)在基线时，3个月或6个月，通过使用患者健康问卷(PHQ-9)确定，专业生活质量(ProQOL)量表，和DSM-5（PCL-5）的PTSD清单。干预措施包括与经过认证的治疗师进行的12次独立的EMDR课程。对照组接受常规护理。该试验有三个主要结果：抑郁症的变化，从随机化到6个月的倦怠和PTSD评分。所有参与者均随访12个月。结论：这项研究提供了有关COVID-19大流行的影响及其对医护人员的心理健康负担的经验证据，并评估了EMDR作为心理干预的有效性。试用登记NCT04570202。
医护人员的压力风险增加，焦虑,抑郁症,COVID-19大流行后的倦怠和创伤后应激障碍。在这项研究中,EMDR在减少抑郁方面的有效性，调查了接触COVID-19的医护人员的倦怠和创伤后应激障碍。在这项研究中,使用原始的“队列内试验”(TwiC)设计,该设计由一项队列研究和一项嵌入式实用随机试验组成.这项研究完全基于网络，包括在线筛查，同意和评估。
医护人员的压力风险增加，焦虑,抑郁症,COVID-19大流行后的倦怠和创伤后应激障碍。在这项研究中,EMDR在减少抑郁方面的有效性，调查了接触COVID-19的医护人员的倦怠和创伤后应激障碍。在这项研究中,使用原始的“队列内试验”(TwiC)设计,该设计由一项队列研究和一项嵌入式实用随机试验组成.这项研究完全基于网络，包括在线筛查，同意和评估。
