Abstract：
Depression prevalence increases significantly during adolescence/early adulthood. Depression in youth may present suicidal ideation, while suicide represents the leading cause of death in this age group. Moreover, adolescents/young adults frequently report sleep complaints that may partially be due to depressive symptoms. Studies on the associations between depression, sleep complaints and suicidality in this age group are limited. We aimed to examine associations between depressive symptoms, sleep complaints and suicidal ideation in a large (n = 2771), representative sample of adolescents (age: 15-17 years, n = 512) and young adults (age: 18-24 years, n = 2259) from the general population in Greece. A telephone structured questionnaire was administered. Depressive symptoms were assessed using the modified Patient Health-7 questionnaire score, while presence of suicidal ideation and sleep complaints were assessed using the ninth and third question of Patient Health-9 questionnaire, respectively. Mediation logistic regression analysis revealed significant direct paths from depressive symptoms to sleep complaints (odds ratio [OR] 1.22, 95% confidence interval [CI] 1.19-1.24; OR 1.21, 95% CI 1.18-1.24) and suicidal ideation (OR 1.18, 95% CI 1.14-1.22; OR 1.18, 95% CI 1.14-1.22), as well as sleep complaints and suicidal ideation (OR 1.82, 95% CI 1.32-2.50; OR 1.91, 95% CI 1.33-2.76) in the total group and in young adults, respectively, but not among adolescents. Moreover, we detected a significant indirect effect of depressive symptoms on suicidal ideation mediated by sleep complaints (18.8%) in young adults. These findings support the hypothesis that treatment of sleep disturbances among youth with depression may independently further reduce suicidal risk.
摘要：
抑郁症患病率在青春期/成年早期显着增加。青年时期的抑郁症可能会产生自杀意念，而自杀是这个年龄段死亡的主要原因。此外，青少年/年轻人经常报告可能部分是由于抑郁症状引起的睡眠问题.抑郁症之间的关联研究，该年龄组的睡眠投诉和自杀倾向有限。我们的目的是研究抑郁症状之间的关联，睡眠投诉和自杀意念大（n=2771），青少年代表性样本(年龄：15-17岁，n=512）和年轻人（年龄：18-24岁，n=2259）来自希腊的普通人群。进行了电话结构化问卷。使用改良的患者健康-7问卷评分评估抑郁症状，虽然使用患者健康-9问卷的第九和第三个问题评估了自杀意念和睡眠投诉的存在，分别。中介逻辑回归分析显示，从抑郁症状到睡眠主诉（比值比[OR]1.22，95％置信区间[CI]1.19-1.24；OR1.21，95％CI1.18-1.24）和自杀意念（OR1.18，95％CI1.14-1.22；OR1.18，95％CI1.14-1.22）。以及睡眠投诉和自杀意念（OR1.82，95％CI1.32-2.50；OR1.91，95％CI1.33-2.76），分别,但不是在青少年中。此外，在年轻人中,我们发现抑郁症状对睡眠主诉介导的自杀意念有显著的间接影响(18.8%).这些发现支持以下假设：在患有抑郁症的年轻人中治疗睡眠障碍可以独立地进一步降低自杀风险。
