Necrotizing Soft Tissue Infections in South Australia: A 15-Year Review.

南澳大利亚的坏死性软组织感染 ： 15 年回顾。

• 影响指数: 4.423
• 发表时间: Apr 2023
• 来源期刊: Open Forum Infect Dis
• DOI: 10.1093/ofid/ofad117
• PMID: 37035499
• 文章类型: Journal Article
• 中科院分区: Q3
• 方向: 医学
• 作者列表: Tam PCK,Kennedy B,Ashokan A

关键词: Fournier’s gangrene; necrotizing fasciitis; necrotizing soft tissue infection

Abstract

Necrotizing soft tissue infections (NSTIs) are associated with high morbidity and mortality. We retrospectively examined the impact of empiric antimicrobials coupled with early surgery on mortality in NSTI. Early surgery independently reduced 30-day mortality (odds ratio, .16; 95% confidence interval, .05-.51; P < .001) that was not further augmented by empiric antimicrobial choice.

摘要

坏死性软组织感染（NSTIs）与高发病率和死亡率相关。我们回顾性研究了经验性抗菌药物与早期手术对NSTI死亡率的影响。早期手术独立降低了30天死亡率(比值比，.16；95%置信区间，.05-.51；P<.001），经验性抗菌药物的选择并未进一步增强。