Abstract：
Sjögren\'s syndrome (SS) is a common systemic autoimmune disease that affects oral health, and consequently oral health-related quality of life (OHRQoL) due to the involvement of exocrine glands.
The present study aimed to evaluate the oral health-related quality of life and oral health indicators in patients with SS in comparison with healthy individuals.
In the case and control groups (45 patients and 45 healthy individuals), questions about demographic data, other systemic disorders, medications, the years of infection, xerostomia, as well as inquiries about the quality of life (Oral Health Impact Profile-14 - OHIP-14) were asked. The patients were evaluated clinically, and oral health indicators, including the plaque index (PI), the gingival index (GI), the sulcus bleeding index (SBI), and the number of decayed, missing and filled teeth (DMFT) were assessed on the Ramfjord teeth. Unstimulated saliva samples from both groups were obtained and weighed. The data was analyzed using IBM SPSS Statistics for Windows, v. 24.0. Quantitative variables were compared between the case and control groups with the use of the independent t test or their nonparametric equivalent (the Mann-Whitney test).
The comparison of the quantitative variables between the study groups showed a statistically significant difference in the OHRQoL scores (p = 0.037) and the unstimulated saliva flow rate (p = 0.002) between the case and control groups. Also, there was a statistically significant difference in the DMFT index between patients with primary and secondary SS in the case group (p = 0.048).
The lower OHRQoL of patients with SS requires more attention and follow-up to solve periodontal and dental problems in this group of patients.
The present study aimed to evaluate the oral health-related quality of life and oral health indicators in patients with SS in comparison with healthy individuals.
In the case and control groups (45 patients and 45 healthy individuals), questions about demographic data, other systemic disorders, medications, the years of infection, xerostomia, as well as inquiries about the quality of life (Oral Health Impact Profile-14 - OHIP-14) were asked. The patients were evaluated clinically, and oral health indicators, including the plaque index (PI), the gingival index (GI), the sulcus bleeding index (SBI), and the number of decayed, missing and filled teeth (DMFT) were assessed on the Ramfjord teeth. Unstimulated saliva samples from both groups were obtained and weighed. The data was analyzed using IBM SPSS Statistics for Windows, v. 24.0. Quantitative variables were compared between the case and control groups with the use of the independent t test or their nonparametric equivalent (the Mann-Whitney test).
The comparison of the quantitative variables between the study groups showed a statistically significant difference in the OHRQoL scores (p = 0.037) and the unstimulated saliva flow rate (p = 0.002) between the case and control groups. Also, there was a statistically significant difference in the DMFT index between patients with primary and secondary SS in the case group (p = 0.048).
The lower OHRQoL of patients with SS requires more attention and follow-up to solve periodontal and dental problems in this group of patients.
摘要：
背景：干燥综合征（SS）是一种常见的全身性自身免疫性疾病，会影响口腔健康，因此，由于外分泌腺的参与，口腔健康相关的生活质量（OHRQoL）。
目的：本研究旨在评估SS患者与健康个体的口腔健康相关生活质量和口腔健康指标。
方法：在病例组和对照组（45名患者和45名健康人）中，关于人口统计数据的问题，其他系统性疾病，药物,感染的岁月，口干症,以及关于生活质量的询问(口腔健康影响概况-14-OHIP-14)。对患者进行了临床评估，和口腔健康指标，包括菌斑指数（PI），牙龈指数(GI)，沟出血指数（SBI），和腐烂的数量，在Ramfjord牙齿上评估缺失和填充牙齿（DMFT）。从两组获得未刺激的唾液样品并称重。使用IBMSPSSStatisticsforWindows分析数据，v.24.0.使用独立t检验或非参数等效（Mann-Whitney检验）比较病例组和对照组之间的定量变量。
结果：研究组之间定量变量的比较显示，病例组和对照组之间的OHRQoL评分（p=0.037）和未刺激唾液流速（p=0.002）有统计学上的显著差异。此外，病例组原发性和继发性SS患者的DMFT指数差异有统计学意义(p=0.048).
结论：SS患者OHRQoL较低，需要更多的关注和随访以解决该组患者的牙周和牙齿问题。
目的：本研究旨在评估SS患者与健康个体的口腔健康相关生活质量和口腔健康指标。
方法：在病例组和对照组（45名患者和45名健康人）中，关于人口统计数据的问题，其他系统性疾病，药物,感染的岁月，口干症,以及关于生活质量的询问(口腔健康影响概况-14-OHIP-14)。对患者进行了临床评估，和口腔健康指标，包括菌斑指数（PI），牙龈指数(GI)，沟出血指数（SBI），和腐烂的数量，在Ramfjord牙齿上评估缺失和填充牙齿（DMFT）。从两组获得未刺激的唾液样品并称重。使用IBMSPSSStatisticsforWindows分析数据，v.24.0.使用独立t检验或非参数等效（Mann-Whitney检验）比较病例组和对照组之间的定量变量。
结果：研究组之间定量变量的比较显示，病例组和对照组之间的OHRQoL评分（p=0.037）和未刺激唾液流速（p=0.002）有统计学上的显著差异。此外，病例组原发性和继发性SS患者的DMFT指数差异有统计学意义(p=0.048).
结论：SS患者OHRQoL较低，需要更多的关注和随访以解决该组患者的牙周和牙齿问题。
