Abstract：
Antioxidants are widely used in the fields of food, medicine, nutraceuticals, and cosmetics. Given their important roles in promoting and maintaining human health, a large number of antioxidants have been reported. Some antioxidant-related databases have been developed; however, the annotation of antioxidants and related information stored in existing databases is incomplete and requires more efficient retrieval methods. This study aimed to develop a manually curated comprehensive antioxidant database (AODB). Currently, it stores 56,666 small molecules tested for antioxidant activity, 1480 antioxidant peptides, and 998 antioxidant proteins, including their structures, names, antioxidant assay records, computable physicochemical and ADMET properties, and sources. AODB supports text search and mining, 2D and 3D chemical structure search, and BLAST-based protein sequence search, enabling users to retrieve antioxidant data quickly and easily. AODB, as a one-stop antioxidant database, can facilitate the exploration of antioxidants and potential applications. AODB is publicly available and updated annually at https://aodb.idruglab.cn/.
摘要：
抗氧化剂广泛应用于食品领域,医学,营养食品，和化妆品。鉴于它们在促进和维护人类健康方面的重要作用，已经报道了大量的抗氧化剂。已经开发了一些与抗氧化剂相关的数据库；然而，存储在现有数据库中的抗氧化剂和相关信息的注释是不完整的，需要更有效的检索方法。本研究旨在开发手动管理的综合抗氧化剂数据库（AODB）。目前,它存储了56,666个抗氧化活性测试的小分子，1480抗氧化肽，和998种抗氧化蛋白，包括它们的结构，names,抗氧化剂测定记录，可计算的物理化学和ADMET特性，和来源。AODB支持文本搜索和挖掘，2D和3D化学结构搜索，和基于BLAST的蛋白质序列搜索，使用户能够快速轻松地检索抗氧化剂数据。AODB,作为一个一站式的抗氧化剂数据库，可以促进抗氧化剂的探索和潜在的应用。AODB是公开可用的，每年更新在https://aodb。无所事事。cn/.
