关键词: axial length outcomes persistent fetal vascular vasculature persistent hyperplastic primary vitreous risk factors vitrectomy

Mesh : Humans Infant, Newborn Infant Child, Preschool Child Retrospective Studies Retinal Detachment Persistent Hyperplastic Primary Vitreous / diagnosis surgery Vitrectomy Treatment Outcome Postoperative Complications

来  源:   DOI:10.3390/ijms24065836   PDF(Pubmed)

Abstract:
This study aims to investigate the outcomes and risk factors associated with poor vision (vision less than counting fingers, 2.0 logMAR, Snellen vision 20/2000) in patients with posterior or combined persistent fetal vasculature (PFV), with or without surgery. We retrospectively reviewed the medical records of patients who were diagnosed with PFV from January 2008 to April 2021. We included 51 eyes of 44 patients who presented with PFV, of which 38 eyes underwent surgical correction (pars plicata/plana vitrectomy, with or without lensectomy, and intraocular lens implantation) at the median age of 6.0 months (range: 0.7 to 82.0). The mean follow-up was 68.8 months ± 38.0 months. The axial length change in the eyes undergoing surgery was significantly higher than the eyes without surgery (p = 0.025). Initial anterior chamber collapse and retinal detachment were associated with poor vision (p = 0.006 and p = 0.002, respectively). In addition, 37% of eyes with posterior or combined PFV had vision better than counting fingers. Surgery for eyes with PFV could result in better eye growth. Visual outcomes remained poor and were associated with the level of macular abnormality. Initial anterior chamber collapse and retinal detachment at presentation were the risk factors for poor visual outcomes. Vitrectomy for selected PFV eyes is valuable and associated with a better cosmetic outcome (better eye growth).
摘要:
本研究旨在调查与视力不良(视力小于数指,2.0logmar,Snellenvision20/2000)在后部或合并的持续性胎儿血管(PFV)患者中,不管有没有手术。我们回顾性回顾了2008年1月至2021年4月诊断为PFV的患者的医疗记录。我们纳入了44例PFV患者的51只眼,其中38只眼接受了手术矫正(plicata/plana玻璃体切除术,有或没有晶状体切除术,和人工晶状体植入术)的中位年龄为6.0个月(范围:0.7至82.0)。平均随访68.8个月±38.0个月。接受手术的眼睛的轴向长度变化显着高于未接受手术的眼睛(p=0.025)。最初的前房塌陷和视网膜脱离与视力不良有关(分别为p=0.006和p=0.002)。此外,37%的后部或合并PFV的眼睛的视力优于数指。对具有PFV的眼睛进行手术可以导致更好的眼睛生长。视力结果仍然很差,并且与黄斑异常水平有关。最初的前房塌陷和视网膜脱离是视力不良的危险因素。选择的PFV眼睛的玻璃体切除术是有价值的,并且与更好的美容结果(更好的眼睛生长)相关。
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