设计,OA - 他克林杂种作为胆碱酯酶抑制剂的合成和评价 , 对阿尔茨海默病具有低神经毒性和肝毒性。
关键词: Alzheimer’s disease Oleanolic acid cholinesterase inhibitors low-toxicity tacrine
Mesh : Humans Tacrine / pharmacology Cholinesterase Inhibitors / pharmacology Alzheimer Disease / drug therapy Acetylcholinesterase / metabolism Structure-Activity Relationship Chemical and Drug Induced Liver Injury
来 源:
DOI:10.1080/14756366.2023.2192439
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