PDF(Pubmed)
Abstract：
The natural history of cirrhosis has usually been conceptualized in the context of progression from compensated cirrhosis to subsequent stages of decompensation. While this unidirectional concept is the most common pathophysiological trajectory, there has been an emerging understanding of a subgroup of patients which undergo recompensation. While literature mostly based on transplant waitlist registries have indicated towards such a population who experience disease regression, the overall literature about this entity remains inexplicit. An effort to generate consensus on defining recompensation has been attempted which comes with its own nuances and limitations. We summarize the available literature on this emerging yet controversial concept of recompensation in cirrhosis and delve into future implications and impact on real-life practice.
摘要：
肝硬化的自然史通常是在从代偿性肝硬化发展到随后的代偿失调阶段的背景下概念化的。虽然这种单向概念是最常见的病理生理轨迹，对接受再补偿的患者亚组有了新的认识.虽然主要基于移植候补名单登记处的文献表明，对于这种经历疾病消退的人群，关于这个实体的整体文献仍然不明确。已尝试就定义补偿达成共识，这具有其自身的细微差别和局限性。我们总结了有关肝硬化中这种新兴但有争议的再补偿概念的现有文献，并深入研究了对现实生活实践的未来影响和影响。
