Abstract：
Saturated fats found in diets known as high-fat, cafeteria, or Western diets appear to have a negative effect on bone structure; however, few studies have focused on investigating this association, and the data available in the literature remain controversial.
The aim of the current review was to investigate the effects of a high-fat dietary intake on the bone structure of Wistar rats.
A search for articles was carried out in the Pubmed/MEDLINE, Web of Science, Embase, and Scopus databases.
In total, 447 articles were found in the initial search; 5 articles were included in the systematic review, after application of the exclusion criteria.
The review was guided by the PICOS strategy and based on the PRISMA protocol for animal reviews.
High-fat diets appear to affect bone structure of Wistar rats. Diet composition and exposure time are the factors determining the strength of the effect.
The aim of the current review was to investigate the effects of a high-fat dietary intake on the bone structure of Wistar rats.
A search for articles was carried out in the Pubmed/MEDLINE, Web of Science, Embase, and Scopus databases.
In total, 447 articles were found in the initial search; 5 articles were included in the systematic review, after application of the exclusion criteria.
The review was guided by the PICOS strategy and based on the PRISMA protocol for animal reviews.
High-fat diets appear to affect bone structure of Wistar rats. Diet composition and exposure time are the factors determining the strength of the effect.
摘要：
背景：在被称为高脂肪的饮食中发现的饱和脂肪，自助餐厅,或西方饮食似乎对骨骼结构有负面影响;然而，很少有研究专注于调查这种关联，文献中的数据仍然存在争议。
目的：本综述的目的是研究高脂肪饮食摄入对Wistar大鼠骨骼结构的影响。
方法：在Pubmed/MEDLINE中进行了文章搜索，WebofScience,Embase,和Scopus数据库。
方法：总共，在最初的搜索中发现了447篇文章；系统综述中包含了5篇文章，在应用排除标准后。
方法：审查以PICOS策略为指导，并基于PRISMA方案进行动物审查。
结论：高脂饮食似乎会影响Wistar大鼠的骨骼结构。饮食组成和暴露时间是决定效果强度的因素。
目的：本综述的目的是研究高脂肪饮食摄入对Wistar大鼠骨骼结构的影响。
方法：在Pubmed/MEDLINE中进行了文章搜索，WebofScience,Embase,和Scopus数据库。
方法：总共，在最初的搜索中发现了447篇文章；系统综述中包含了5篇文章，在应用排除标准后。
方法：审查以PICOS策略为指导，并基于PRISMA方案进行动物审查。
结论：高脂饮食似乎会影响Wistar大鼠的骨骼结构。饮食组成和暴露时间是决定效果强度的因素。
