PDF(Pubmed)
Abstract：
UNASSIGNED: melasma is a common acquired hypermelanosis which occurs mostly in face that caused by many factors. One of the pathogenesis of melasma in men is affected by testosterone. This study aimed to investigate the relationship between testosterone levels and melasma in men and its association with the severity of melasma as measured by the melasma area and severity index (MASI) score.
UNASSIGNED: a case-control study involving 30 subjects with melasma and 30 subjects without melasma who were treated at the outpatient clinic of Dermatovenereology of Ngoerah General Hospital from June to August 2022. Descriptive statistical analysis is to determine frequencies and percentages. Bivariate analysis was used to find any risk factor between testosterone level and melasma. Data obtained from the two groups then analyzed for correlation between the MASI score and testosterone levels.
UNASSIGNED: mean age of the subjects in the melasma group was 43.83±6.30 and in control group was 43.80±6.09. Mean testosterone level in the melasma group (7.55±1.77) was significantly lower than the control group (21.07±6.65; p = 0.001). Subject with testosterone level ≥8.92 nmol/L has 6.9 times risk of melasma compare to control (aOR: 6.986, 95% CI 1.905-25.622; p = 0.003).
UNASSIGNED: low testosterone levels possibly have a role in pathogenesis of melasma in men.
UNASSIGNED: a case-control study involving 30 subjects with melasma and 30 subjects without melasma who were treated at the outpatient clinic of Dermatovenereology of Ngoerah General Hospital from June to August 2022. Descriptive statistical analysis is to determine frequencies and percentages. Bivariate analysis was used to find any risk factor between testosterone level and melasma. Data obtained from the two groups then analyzed for correlation between the MASI score and testosterone levels.
UNASSIGNED: mean age of the subjects in the melasma group was 43.83±6.30 and in control group was 43.80±6.09. Mean testosterone level in the melasma group (7.55±1.77) was significantly lower than the control group (21.07±6.65; p = 0.001). Subject with testosterone level ≥8.92 nmol/L has 6.9 times risk of melasma compare to control (aOR: 6.986, 95% CI 1.905-25.622; p = 0.003).
UNASSIGNED: low testosterone levels possibly have a role in pathogenesis of melasma in men.
摘要：
未经证实：黄褐斑是一种常见的获得性黑色素沉着症，主要发生在面部，由多种因素引起。男性黄褐斑的发病机制之一是受睾酮的影响。本研究旨在通过黄褐斑面积和严重程度指数（MASI）评分，探讨男性睾酮水平与黄褐斑的关系及其与黄褐斑严重程度的关系。
UNASSIGNED：一项病例对照研究，涉及30名黄褐斑患者和30名无黄褐斑患者，于2022年6月至8月在Ngoerah总医院皮肤性病科门诊接受治疗。描述性统计分析是确定频率和百分比。双变量分析用于发现睾酮水平和黄褐斑之间的任何危险因素。从两组获得的数据然后分析MASI评分和睾酮水平之间的相关性。
未经证实：黄褐斑组受试者的平均年龄为43.83±6.30，对照组为43.80±6.09。黄褐斑组的平均睾酮水平（7.55±1.77）明显低于对照组（21.07±6.65；p=0.001）。睾酮水平≥8.92nmol/L的受试者黄褐斑的风险是对照组的6.9倍(aOR:6.986,95%CI1.905-25.622;p=0.003)。
未经证实：低睾酮水平可能在男性黄褐斑的发病机制中起作用。
UNASSIGNED：一项病例对照研究，涉及30名黄褐斑患者和30名无黄褐斑患者，于2022年6月至8月在Ngoerah总医院皮肤性病科门诊接受治疗。描述性统计分析是确定频率和百分比。双变量分析用于发现睾酮水平和黄褐斑之间的任何危险因素。从两组获得的数据然后分析MASI评分和睾酮水平之间的相关性。
未经证实：黄褐斑组受试者的平均年龄为43.83±6.30，对照组为43.80±6.09。黄褐斑组的平均睾酮水平（7.55±1.77）明显低于对照组（21.07±6.65；p=0.001）。睾酮水平≥8.92nmol/L的受试者黄褐斑的风险是对照组的6.9倍(aOR:6.986,95%CI1.905-25.622;p=0.003)。
未经证实：低睾酮水平可能在男性黄褐斑的发病机制中起作用。
