PDF(Pubmed)
Abstract：
UNASSIGNED: schistosomiasis is a neglected parasitic infection caused by nematode worms. It affects approximately 200 million people globally. Prevalence in Ghana is 23.3%, mostly affecting school children. On November 28th 2018, the Disease Surveillance Department received reports of increase in occurrence of bloody urine among students of a basic school in the Volta Region. We investigated to identify the agent and source, to determine the magnitude, risk factors and to implement control measures.
UNASSIGNED: we conducted a case-control study. A suspected case was any student of the school, who has bloody urine with or without: dysuria, itching of the skin, frequent urination or lower abdominal pain from September 2018 to November 2018. A confirmed case was one with laboratory-isolation of Schistosoma ova in appropriate urine sample. We identified cases from the school and hospital records. We collected socio-demographic, clinical and exposure data from cases and controls. Descriptive and inferential analysis were performed to estimate odds ratios at 95% confidence intervals (CI) to determine associations.
UNASSIGNED: of 880 students, 112 suspected cases were identified (attack rate = 12.7%). Mean age of suspected cases was 14-years (standard deviation = ±3.5). Confirmed cases were 76.8%(86/112). Males had twice odds of becoming cases (cOR = 2.3, 95% CI = 1.35-3.96). Fishing (cOR = 7.29, 95% CI = 4.08-13.04) and swimming (aOR = 44.63, 95% CI = 4.73-420.86) were factors significantly associated with infection. Students with previous history of bloody urine had greater odds of being cases (aOR = 47.9, 95% CI = 4.19-546.55).
UNASSIGNED: Schistosoma haematobium was isolated in this outbreak. Fishing and swimming were risky water-related activities. WASH education and mass drug administration with Praziquantel were control measures.
UNASSIGNED: we conducted a case-control study. A suspected case was any student of the school, who has bloody urine with or without: dysuria, itching of the skin, frequent urination or lower abdominal pain from September 2018 to November 2018. A confirmed case was one with laboratory-isolation of Schistosoma ova in appropriate urine sample. We identified cases from the school and hospital records. We collected socio-demographic, clinical and exposure data from cases and controls. Descriptive and inferential analysis were performed to estimate odds ratios at 95% confidence intervals (CI) to determine associations.
UNASSIGNED: of 880 students, 112 suspected cases were identified (attack rate = 12.7%). Mean age of suspected cases was 14-years (standard deviation = ±3.5). Confirmed cases were 76.8%(86/112). Males had twice odds of becoming cases (cOR = 2.3, 95% CI = 1.35-3.96). Fishing (cOR = 7.29, 95% CI = 4.08-13.04) and swimming (aOR = 44.63, 95% CI = 4.73-420.86) were factors significantly associated with infection. Students with previous history of bloody urine had greater odds of being cases (aOR = 47.9, 95% CI = 4.19-546.55).
UNASSIGNED: Schistosoma haematobium was isolated in this outbreak. Fishing and swimming were risky water-related activities. WASH education and mass drug administration with Praziquantel were control measures.
摘要：
未经证实：血吸虫病是由线虫引起的一种被忽视的寄生虫感染。它影响了全球约2亿人。加纳的患病率为23.3％，主要影响学童。2018年11月28日，疾病监测部门收到了有关Volta地区一所基础学校学生血尿增加的报告。我们进行了调查以确定代理人和来源，为了确定大小，风险因素并实施控制措施。
未经评估：我们进行了病例对照研究。疑似病例是学校的任何学生，有或没有血尿的人:排尿困难，皮肤瘙痒，2018年9月至2018年11月尿频或下腹痛。确诊病例是在适当的尿液样本中实验室分离血吸虫卵的病例。我们从学校和医院记录中确定了病例。我们收集了社会人口统计，来自病例和对照的临床和暴露数据。进行描述性和推断性分析，以95％置信区间（CI）估计比值比，以确定关联。
未经评估：880名学生，确定了112例疑似病例（发作率=12.7%）。疑似病例的平均年龄为14岁（标准差=±3.5）。确诊病例占76.8%(86/112)。男性有两倍的几率成为病例(cOR=2.3，95%CI=1.35-3.96)。钓鱼（cOR=7.29，95％CI=4.08-13.04）和游泳（aOR=44.63，95％CI=4.73-420.86）是与感染显着相关的因素。既往有血尿史的学生有更大的病例几率(aOR=47.9,95%CI=4.19-546.55)。
UnASSIGNED：这次疫情分离出了血吸虫。钓鱼和游泳是与水有关的危险活动。WASH教育和吡喹酮的大规模药物管理是控制措施。
未经评估：我们进行了病例对照研究。疑似病例是学校的任何学生，有或没有血尿的人:排尿困难，皮肤瘙痒，2018年9月至2018年11月尿频或下腹痛。确诊病例是在适当的尿液样本中实验室分离血吸虫卵的病例。我们从学校和医院记录中确定了病例。我们收集了社会人口统计，来自病例和对照的临床和暴露数据。进行描述性和推断性分析，以95％置信区间（CI）估计比值比，以确定关联。
未经评估：880名学生，确定了112例疑似病例（发作率=12.7%）。疑似病例的平均年龄为14岁（标准差=±3.5）。确诊病例占76.8%(86/112)。男性有两倍的几率成为病例(cOR=2.3，95%CI=1.35-3.96)。钓鱼（cOR=7.29，95％CI=4.08-13.04）和游泳（aOR=44.63，95％CI=4.73-420.86）是与感染显着相关的因素。既往有血尿史的学生有更大的病例几率(aOR=47.9,95%CI=4.19-546.55)。
UnASSIGNED：这次疫情分离出了血吸虫。钓鱼和游泳是与水有关的危险活动。WASH教育和吡喹酮的大规模药物管理是控制措施。
