PDF(Pubmed)
Abstract：
UNASSIGNED: Following propofol induction, suxamethonium tremendously improves intubating conditions in children and has been the gold standard agent for this purpose. However, suxamethonium could be absolutely contraindicated in some patients. Fentanyl, a short acting opioid, has been investigated as a suitable alternative with varying results.
UNASSIGNED: This study compares the ease of tracheal intubation between propofol-suxamethonium (1.5 mg/kg) and propofol-fentanyl (3 mcg/kg) during general anaesthesia among children.
UNASSIGNED: In this double-blind randomised controlled study, 84 ASA I or II patients booked for elective surgery under general anaesthesia requiring tracheal intubation were randomised into two groups (F and S). Induction was with propofol 3 mg/kg over 30 s followed by either fentanyl 3 mcg/kg or suxamethonium 1.5 mg/kg. Two minutes later, there was an attempt at intubation and intubating conditions were assessed using Steyn\'s modification of Helbo-Hansen\'s score (ease of laryngoscopy, jaw relaxation, coughing, vocal cord position, and limb movement).
UNASSIGNED: All patients in both groups had successful intubation at the first attempt. Patients in group S (suxamethonium) had significantly better overall intubating conditions compared to those in group F (fentanyl) (p=0.0001), 85.7% in group S compared to 21.4% in group F had excellent intubation condition. None of the patients in the two groups demonstrated fair or poor intubation condition.
UNASSIGNED: A combination of propofol-fentanyl can be used as an alternative to propofol-suxamethonium to ease intubation in paediatric patients.
UNASSIGNED: This study compares the ease of tracheal intubation between propofol-suxamethonium (1.5 mg/kg) and propofol-fentanyl (3 mcg/kg) during general anaesthesia among children.
UNASSIGNED: In this double-blind randomised controlled study, 84 ASA I or II patients booked for elective surgery under general anaesthesia requiring tracheal intubation were randomised into two groups (F and S). Induction was with propofol 3 mg/kg over 30 s followed by either fentanyl 3 mcg/kg or suxamethonium 1.5 mg/kg. Two minutes later, there was an attempt at intubation and intubating conditions were assessed using Steyn\'s modification of Helbo-Hansen\'s score (ease of laryngoscopy, jaw relaxation, coughing, vocal cord position, and limb movement).
UNASSIGNED: All patients in both groups had successful intubation at the first attempt. Patients in group S (suxamethonium) had significantly better overall intubating conditions compared to those in group F (fentanyl) (p=0.0001), 85.7% in group S compared to 21.4% in group F had excellent intubation condition. None of the patients in the two groups demonstrated fair or poor intubation condition.
UNASSIGNED: A combination of propofol-fentanyl can be used as an alternative to propofol-suxamethonium to ease intubation in paediatric patients.
摘要：
未经批准：异丙酚诱导后，suxamethonium极大地改善了儿童的插管条件，并且一直是用于此目的的金标准剂。然而,在某些患者中，suxamethonium可能是绝对禁忌的。芬太尼,一种短效的阿片类药物，已作为一种合适的替代方案进行了研究，结果各不相同。
UNASSIGNED：这项研究比较了儿童全身麻醉时丙泊酚-suxamethium（1.5mg/kg）和丙泊酚-芬太尼（3mcg/kg）气管插管的方便性。
未经评估：在这项双盲随机对照研究中，84名在全身麻醉下需要气管插管的择期手术的ASAI或II患者被随机分为两组（F和S）。在30s内使用丙泊酚3mg/kg进行诱导，然后使用芬太尼3mcg/kg或甲胺1.5mg/kg。两分钟后,曾尝试插管,使用Steyn修改的Helbo-Hansen评分(喉镜检查的简易程度,下巴放松,咳嗽,声带位置,和肢体运动）。
UNASSIGNED：两组患者首次插管均成功。与F组（芬太尼）相比，S组（suxamethonium）患者的总体插管条件明显更好（p=0.0001），S组为85.7%,F组为21.4%,插管情况良好。两组患者均未表现出一般或较差的插管条件。
UNASSIGNED：丙泊酚-芬太尼的组合可以用作丙泊酚-舒沙胺铵的替代品，以缓解儿科患者的插管。
UNASSIGNED：这项研究比较了儿童全身麻醉时丙泊酚-suxamethium（1.5mg/kg）和丙泊酚-芬太尼（3mcg/kg）气管插管的方便性。
未经评估：在这项双盲随机对照研究中，84名在全身麻醉下需要气管插管的择期手术的ASAI或II患者被随机分为两组（F和S）。在30s内使用丙泊酚3mg/kg进行诱导，然后使用芬太尼3mcg/kg或甲胺1.5mg/kg。两分钟后,曾尝试插管,使用Steyn修改的Helbo-Hansen评分(喉镜检查的简易程度,下巴放松,咳嗽,声带位置,和肢体运动）。
UNASSIGNED：两组患者首次插管均成功。与F组（芬太尼）相比，S组（suxamethonium）患者的总体插管条件明显更好（p=0.0001），S组为85.7%,F组为21.4%,插管情况良好。两组患者均未表现出一般或较差的插管条件。
UNASSIGNED：丙泊酚-芬太尼的组合可以用作丙泊酚-舒沙胺铵的替代品，以缓解儿科患者的插管。
