关键词: Clinical stage Germ cell tumor Lymphovascular invasion Pathologic stage Rete testis invasion Spermatic cord involvement Testis cancer

Mesh : Adult Male Humans Young Adult Testicular Neoplasms / therapy pathology Neoplasm Staging Neoplasm Invasiveness / pathology Neoplasms, Germ Cell and Embryonal / therapy pathology Orchiectomy

来  源:   DOI:10.1016/j.humpath.2023.02.010

Abstract:
Testicular cancer is the most common solid neoplasm of adult men between the ages of 20 and 40 years. Germ cell tumors account for 95% of all testicular tumors. The assessment of staging is essential to guide further management of patients with testicular cancer and to prognosticate cancer-related outcomes. Postradical orchiectomy treatment options, including adjuvant therapy and active surveillance, vary based on the anatomical extent of disease, serum tumor markers, pathologic diagnosis, and imaging. This review provides an update on the germ cell tumor staging system adopted by the 8th edition of the American Joint Commission on Cancer (AJCC) Staging Manual, treatment implications, risk factors, and predictors of outcomes.
摘要:
睾丸癌是20至40岁成年男性最常见的实体瘤。生殖细胞肿瘤占所有睾丸肿瘤的95%。分期评估对于指导睾丸癌患者的进一步治疗和预测癌症相关结局至关重要。睾丸切除术后的治疗选择,包括辅助治疗和主动监测,根据疾病的解剖范围而变化,血清肿瘤标志物,病理诊断,和成像。这篇评论提供了美国癌症联合委员会(AJCC)分期手册第8版采用的生殖细胞肿瘤分期系统的更新,治疗意义,危险因素,和结果的预测因素。
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