PDF(Pubmed)
Abstract：
Hyperostosis Frontalis Interna (HFI), a condition that has been sparsely explained till now, is a benign, asymptomatic, and irregular thickening of the endocranium of the frontal bone. It is found to be predominantly present in post-menopausal women during incidental X-ray or CT/MRI of the skull. The prevalence of HFI is documented in different populations, but in the Indian population, it is comparatively rare. Thus, we discuss a serendipitous finding of HFI in an Indian skull. This rare variation was noted in dry Indian human skulls. Gross features of the skull were noted, and it was an adult female skull. The area was decalcified, paraffin-embedded, and stained with Haematoxylin and Eosin. The skull bone was also subjected to plain X-ray/CT investigation. The X-ray skull of 50+ year female type features in anteroposterior and lateral view showed widening of the diploic spaces 8-10 mm with ill-defined hyperdense areas in the frontal region. Changes in computed tomography were noted. HFI often has nonspecific and benign symptoms. However, in severe cases, widespread clinical implications starting from headache, motor aphasia, parkinsonism, and depression can occur, and thus we all should be aware of it.
摘要：
额骨肥大症（HFI），到现在为止已经被稀疏地解释的情况，是良性的，无症状，额骨内膜不规则增厚。在颅骨的偶然X射线或CT/MRI中，发现主要存在于绝经后妇女中。HFI的患病率记录在不同的人群中，但是在印度人口中，比较少见。因此，我们讨论了在印度头骨中偶然发现的HFI。在干燥的印度人类头骨中发现了这种罕见的变化。注意到头骨的大体特征，那是一个成年女性头骨.这个地区脱钙了,石蜡包埋，并用苏木精和伊红染色。颅骨也进行了X线/CT检查。在前后和侧向视图中，50年女性类型的X射线颅骨特征显示，二倍体空间扩大了8-10mm，额叶区域的高密度区域不明确。注意到计算机断层扫描的变化。HFI通常具有非特异性和良性症状。然而,在严重的情况下，从头痛开始的广泛临床意义，运动性失语症,帕金森病,抑郁症也会发生，因此我们都应该意识到这一点。
