关键词: Complication Corticosteroids Cryptococcal meningitis Therapy Underlying diseases

Mesh : Humans Meningitis, Cryptococcal / drug therapy AIDS-Related Opportunistic Infections / drug therapy HIV Infections / drug therapy Antifungal Agents / therapeutic use Adrenal Cortex Hormones / therapeutic use

来  源:   DOI:10.1016/j.mycmed.2023.101364

Abstract:
Cryptococcal meningitis (CM) is a serious disease with high morbidity and mortality. Although the patients who received corticosteroids were at high risk of having CM, corticosteroids also have been used as an adjunct to antifungal drugs for treating people with CM in some situations (such as immune reconstitution inflammatory syndrome, cerebral cyptococcoma, et al.). Here, we summarize the current knowledge on the application of the corticosteroids in CM, aiming to help clinicians to reasonably use corticosteroids in patients with CM.
摘要:
隐球菌性脑膜炎(CM)是一种发病率和死亡率高的严重疾病。虽然接受皮质类固醇的患者有很高的CM风险,在某些情况下,皮质类固醇还被用作抗真菌药物的辅助药物,用于治疗CM患者(例如免疫重建炎症综合征,脑型CT,etal.).这里,我们总结了目前关于糖皮质激素在CM中应用的知识,旨在帮助临床医生合理使用CM患者的糖皮质激素。
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