关键词: Dessie Ethiopia HIV/AIDS Quality of sleep Sleep disturbance

Mesh : Adult Female Humans Male HIV Infections / complications drug therapy Sleep Quality Cross-Sectional Studies Ethiopia / epidemiology Follow-Up Studies Ambulatory Care Facilities

来  源:   DOI:10.1186/s12888-023-04619-w

Abstract:
Poor sleep quality is an important health problem in people living with HIV. The exact cause of sleep disturbance is not well known, but it may relate to HIV itself, antiretroviral drug side effects, and other HIV-related disorders. As a result, the purpose of this study was to assess sleep quality and associated factors among adult HIV patients on follow-up at Dessie Town governmental health facilities\' antiretroviral therapy clinics in Northeast Ethiopia in 2020.
A multi-center cross-sectional study was conducted among 419 adult people living with HIV/AIDS from February 1/2020 to April 22/2020 in Dessie Town governmental antiretroviral therapy clinics. A systematic random sampling method was used to select the study participants. An interviewer-administered method of data collection with a chart review was used. The Pittsburgh Sleep Quality Index was used to evaluate sleep disruption. A binary logistic regression was conducted to see the relationship between a dependent variable and independent variables. Variables with a p-value of < 0.05 and a 95% confidence interval were used to declare an association between factors and a dependent variable.
A total of 419 study participants were enrolled in this study, with a response rate of 100%. The mean age of the study participants was 36 ± 6.5 SD years and 63.7% of the participants were female. The prevalence of poor sleep quality was found to be 36% (95% CI, 31-41%). Being female (AOR = 3.45, 95% CI: 1.52-7.79), viral loads 1000 copies/ml (AOR = 6.88, 95% CI: 2.79-16.9), CD4 cell count 200 cells/mm3 (AOR = 6.85, 95% CI: 2.42-19.39), WHO stage II and III (AOR = 4.29, 95% CI: 1.05-17.53), having anxiety (AOR = 10, 95% CI: 4.21-23.9.
The findings of this study showed that more than one-third of the study participants had poor-quality sleep at the Dessie Town Health Facility ART clinic. Being female, low CD4 cell counts, viral load ≥1000 copies/ml, WHO stage II and III, depression, anxiety, sleeping in a communal bedroom, and living alone were predictors of poor sleep quality.
摘要:
背景:睡眠质量差是艾滋病毒感染者的一个重要健康问题。睡眠障碍的确切原因尚不清楚,但它可能与艾滋病毒本身有关,抗逆转录病毒药物副作用,和其他与艾滋病毒有关的疾病。因此,这项研究的目的是评估2020年在埃塞俄比亚东北部Dessie镇政府医疗机构抗逆转录病毒治疗诊所随访的成年HIV患者的睡眠质量和相关因素。
方法:一项多中心横断面研究于2020年2月1日至2020年4月22日在德西镇政府抗逆转录病毒治疗诊所对419名感染艾滋病毒/艾滋病的成年人进行。采用系统随机抽样方法选择研究参与者。使用了面试官管理的数据收集方法,并进行了图表审查。匹兹堡睡眠质量指数用于评估睡眠中断。进行二元逻辑回归以查看因变量和自变量之间的关系。使用p值<0.05和95%置信区间的变量来声明因子与因变量之间的关联。
结果:本研究共纳入419名研究参与者,响应率为100%。研究参与者的平均年龄为36±6.5SD岁,63.7%的参与者为女性。睡眠质量差的患病率为36%(95%CI,31-41%)。女性(AOR=3.45,95%CI:1.52-7.79),病毒载量1000拷贝/毫升(AOR=6.88,95%CI:2.79-16.9),CD4细胞计数200个细胞/mm3(AOR=6.85,95%CI:2.42-19.39),WHOII期和III期(AOR=4.29,95%CI:1.05-17.53),有焦虑(AOR=10,95%CI:4.21-23.9。
结论:这项研究的结果表明,超过三分之一的研究参与者在DessieTownHealthFacilityART诊所的睡眠质量较差。作为女性,低CD4细胞计数,病毒载量≥1000拷贝/毫升,世卫组织第二阶段和第三阶段,抑郁症,焦虑,睡在公共卧室里,和独居是睡眠质量差的预测因素。
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