Abstract：
Time elapsed since pain onset might affect the likelihood of neuropathic component in low back pain. The aim of this study was to investigate the relationship between neuropathic pain component and pain duration in patients with low back pain and to identify factors associated with neuropathic pain component.
Patients with low back pain who received treatment at our clinic were enrolled. Neuropathic component was assessed using the painDETECT questionnaire at the initial visit. PainDETECT scores and the results for each item were compared according to pain duration category (< 3 months, 3 months to 1 year, 1 year to 3 years, 3 years to 10 years, and ≥ 10 years). A multivariate analysis was used to identify factors associated with neuropathic pain component (painDETECT score ≥ 13) in low back pain.
A total of 1957 patients, including 255 patients who reported neuropathic-like pain symptoms (13.0%), fully satisfied the study criteria for analysis. No significant correlation between painDETECT score and pain duration was observed (ρ = -0.025, p = 0.272), and there were no significant differences between median painDETECT score or trend of change in the proportion of patients with neuropathic component and the pain duration category (p = 0.307, p = 0.427, respectively). The electric shock-like pain symptom was frequently reported in patients with acute low back pain, and the persistent pain pattern with slight fluctuations was predominant in chronic low back pain. The pattern of attacks with pain between them was much less common in patients with pain for 10 years or longer. Multivariate analysis revealed that a history of lumbar surgery, severe maximum pain, opioid use, lumbosacral radiculopathy, and sleep disturbance were significantly associated with a neuropathic component in low back pain.
Time elapsed since current pain onset did not correlate with neuropathic pain component in patients with low back pain. Therefore, diagnostic and therapeutic approaches for this condition should be based on a multidimensional evaluation at assessment and not on pain duration alone.
Patients with low back pain who received treatment at our clinic were enrolled. Neuropathic component was assessed using the painDETECT questionnaire at the initial visit. PainDETECT scores and the results for each item were compared according to pain duration category (< 3 months, 3 months to 1 year, 1 year to 3 years, 3 years to 10 years, and ≥ 10 years). A multivariate analysis was used to identify factors associated with neuropathic pain component (painDETECT score ≥ 13) in low back pain.
A total of 1957 patients, including 255 patients who reported neuropathic-like pain symptoms (13.0%), fully satisfied the study criteria for analysis. No significant correlation between painDETECT score and pain duration was observed (ρ = -0.025, p = 0.272), and there were no significant differences between median painDETECT score or trend of change in the proportion of patients with neuropathic component and the pain duration category (p = 0.307, p = 0.427, respectively). The electric shock-like pain symptom was frequently reported in patients with acute low back pain, and the persistent pain pattern with slight fluctuations was predominant in chronic low back pain. The pattern of attacks with pain between them was much less common in patients with pain for 10 years or longer. Multivariate analysis revealed that a history of lumbar surgery, severe maximum pain, opioid use, lumbosacral radiculopathy, and sleep disturbance were significantly associated with a neuropathic component in low back pain.
Time elapsed since current pain onset did not correlate with neuropathic pain component in patients with low back pain. Therefore, diagnostic and therapeutic approaches for this condition should be based on a multidimensional evaluation at assessment and not on pain duration alone.
摘要：
背景：自疼痛发作以来经过的时间可能会影响下背痛中神经性成分的可能性。这项研究的目的是调查下腰痛患者的神经性疼痛成分与疼痛持续时间之间的关系，并确定与神经性疼痛成分相关的因素。
方法：纳入在我们诊所接受治疗的腰背痛患者。在初次就诊时使用疼痛检测问卷评估神经病变成分。根据疼痛持续时间类别（<3个月，3个月至1年,1年至3年,3年到10年,且≥10年)。多变量分析用于确定与下腰痛的神经性疼痛成分（painDETECT评分≥13）相关的因素。
结果：总共1957名患者，包括255名报告有神经性疼痛症状的患者（13.0%），完全满足分析的研究标准。观察到疼痛DETECT评分与疼痛持续时间之间没有显着相关性（ρ=-0.025，p=0.272），并且在有神经病变成分的患者比例和疼痛持续时间类别的中位疼痛DETECT评分或变化趋势之间没有显着差异（分别为p=0.307，p=0.427）。急性下腰痛患者常出现电击样疼痛症状，慢性腰背痛以轻微波动的持续性疼痛模式为主。在疼痛持续10年或更长时间的患者中，它们之间的疼痛发作模式并不常见。多因素分析显示腰椎手术史,严重的最大疼痛，阿片类药物的使用，腰骶神经根病,和睡眠障碍与下腰痛的神经性成分显着相关。
结论：下腰痛患者自当前疼痛发作以来经过的时间与神经性疼痛成分无关。因此,这种情况的诊断和治疗方法应基于评估时的多维评估，而不仅仅是疼痛持续时间。
方法：纳入在我们诊所接受治疗的腰背痛患者。
结果：总共1957名患者，
结论：下腰痛患者自当前疼痛发作以来经过的时间与神经性疼痛成分无关。
