Abstract：
To summarize changes in recommendations for injection treatments for knee osteoarthritis (OA) in current clinical practice guidelines (CPGs) and to assess whether these changes have affected public interest according to Google data and content in YouTube videos.
A literature search to identify CPGs revised since 2019 that provide recommendations regarding the five intra-articular injection treatments for knee OA (corticosteroid [CS], hyaluronic acid [HA], stem cell [SC], platelet-rich plasma [PRP], and botulinum toxin [BT]) was conducted to assess perspective changes for each treatment. Data from Google Trends were examined to identify changes in search volume from 2004 to 2021 using a join-point regression model. Relevant YouTube videos were divided into those uploaded before and after changes in CPGs and compared according to degrees of recommendation for each treatment to identify the effect of changes in CPGs on video production.
All eight identified CPGs released after 2019 recommended HA and CS use. Most CPGs were the first to state a neutral or opposing stance concerning the use of SC, PRP, or BT. Interestingly, relative searches on Google for SC, PRP, and BT has increased greater than those for CS and HA. YouTube videos produced after CPGs changed continue to recommend SC, PRP, and BT as much as those produced before CPGs were revised.
Although knee OA CPGs have changed, public interest and healthcare information providers on YouTube have not reacted to this shift. Improved methods to propagate updates to CPGs warrant consideration.
A literature search to identify CPGs revised since 2019 that provide recommendations regarding the five intra-articular injection treatments for knee OA (corticosteroid [CS], hyaluronic acid [HA], stem cell [SC], platelet-rich plasma [PRP], and botulinum toxin [BT]) was conducted to assess perspective changes for each treatment. Data from Google Trends were examined to identify changes in search volume from 2004 to 2021 using a join-point regression model. Relevant YouTube videos were divided into those uploaded before and after changes in CPGs and compared according to degrees of recommendation for each treatment to identify the effect of changes in CPGs on video production.
All eight identified CPGs released after 2019 recommended HA and CS use. Most CPGs were the first to state a neutral or opposing stance concerning the use of SC, PRP, or BT. Interestingly, relative searches on Google for SC, PRP, and BT has increased greater than those for CS and HA. YouTube videos produced after CPGs changed continue to recommend SC, PRP, and BT as much as those produced before CPGs were revised.
Although knee OA CPGs have changed, public interest and healthcare information providers on YouTube have not reacted to this shift. Improved methods to propagate updates to CPGs warrant consideration.
摘要：
目的：总结当前临床实践指南（CPGs）中对膝骨关节炎（OA）注射治疗建议的变化，并根据Google数据和YouTube视频中的内容评估这些变化是否影响了公众利益。
方法：文献检索，以确定自2019年以来修订的CPG，这些CPG提供了有关膝关节OA的五种关节内注射治疗方法的建议（皮质类固醇[CS]，透明质酸[HA]，干细胞[SC]，富血小板血浆[PRP]，和肉毒杆菌毒素[BT]）进行评估，以评估每种治疗的观点变化。使用连接点回归模型检查了Google趋势的数据，以确定2004年至2021年搜索量的变化。将相关的YouTube视频分为CPG变化前后上传的视频，并根据每种治疗的推荐程度进行比较，以确定CPG变化对视频制作的影响。
结果：2019年之后发布的所有8个确定的CPG都推荐使用HA和CS。大多数CPG首先对使用SC表示中立或反对立场，PRP,或者BT。有趣的是,在Google上搜索SC，PRP,BT的增幅大于CS和HA。CPG更改后制作的YouTube视频继续推荐SC，PRP,BT和CPG修订前生产的一样多。
结论：尽管膝关节OACPG发生了变化，YouTube上的公共利益和医疗保健信息提供商没有对这一转变做出反应。将更新传播到CPG的改进方法值得考虑。
方法：文献检索，以确定自2019年以来修订的CPG，这些CPG提供了有关膝关节OA的五种关节内注射治疗方法的建议（皮质类固醇[CS]，
结果：2019年之后发布的所有8个确定的CPG都推荐使用HA和CS。
结论：尽管膝关节OACPG发生了变化，
