Abstract：
BACKGROUND: Ehlers-Danlos syndrome (EDS) is a group of connective tissue disorders of altered collagen synthesis. People with vascular EDS are at increased risk for vascular and hollow viscous rupture. Heavy menstrual bleeding (HMB) is common among adolescents with EDS. The levonorgestrel intrauterine device (LNG-IUD) is an effective treatment option for HMB; however, its use in patients with vascular EDS has historically been avoided due to perceived risk of uterine rupture. This is the first known case report on use of the LNG-IUD in an adolescent with vascular EDS.
METHODS: A 16-year-old female with vascular EDS and HMB underwent placement of the LNG-IUD. Placement of the device was performed in the operating room under ultrasound guidance. At the 6-month follow-up, the patient reported significant improvement in bleeding and high satisfaction. No complications were identified at the time of placement or follow-up.
CONCLUSIONS: LNG-IUD may be a safe and effective option for menstrual management in individuals with vascular EDS.
METHODS: A 16-year-old female with vascular EDS and HMB underwent placement of the LNG-IUD. Placement of the device was performed in the operating room under ultrasound guidance. At the 6-month follow-up, the patient reported significant improvement in bleeding and high satisfaction. No complications were identified at the time of placement or follow-up.
CONCLUSIONS: LNG-IUD may be a safe and effective option for menstrual management in individuals with vascular EDS.
摘要：
背景：Ehlers-Danlos综合征（EDS）是一组胶原合成改变的结缔组织疾病。血管EDS患者血管和中空粘性破裂的风险增加。重度月经出血(HMB)在患有EDS的青少年中很常见。左炔诺孕酮宫内节育器（LNG-IUD）是HMB的有效治疗选择；然而，由于认为有子宫破裂的风险,其在血管EDS患者中的使用历来被避免.这是关于在患有血管性EDS的青少年中使用LNG-IUD的第一个已知病例报告。
方法：患有血管EDS和HMB的16岁女性接受了LNG-IUD的放置。在超声引导下在手术室中进行设备的放置。在六个月的随访中，患者报告出血明显改善,满意度高.在放置或随访时没有发现并发症。
结论：LNG-IUD可能是血管型EDS患者月经管理的安全有效选择。
方法：患有血管EDS和HMB的16岁女性接受了LNG-IUD的放置。
结论：LNG-IUD可能是血管型EDS患者月经管理的安全有效选择。
