Abstract：
Biomimetic zinc-carbonate hydroxyapatite technology was developed to realize materials that mimic the natural hydroxyapatite of enamel and dentin and possess good activity in terms of affinity to adhere to these biological tissues. The chemical and physical characteristics of this active ingredient allows the hydroxyapatite itself to be particularly similar to dental hydroxyapatite, enhancing the bond between biomimetic hydroxyapatite and dental hydroxyapatite. The aim of this review is to assess the efficacy of this technology in terms of benefits for enamel and dentin and reduction of dental hypersensitivity.
METHODS: A literature search (Pubmed/MEDLINE and Scopus) of articles from 2003 to 2023 was conducted to analyze studies focused on the use of zinc-hydroxyapatite products. Duplicates were eliminated from the 5065 articles found, leaving 2076 articles. Of these, 30 articles were analyzed based on the use of products with zinc-carbonate hydroxyapatite in these studies.
RESULTS: 30 articles were included. Most of the studies showed benefits in terms of remineralization and prevention of enamel demineralization in terms of occlusion of the dentinal tubules and reduction of dentinal hypersensitivity.
CONCLUSIONS: Oral care products such as toothpaste and mouthwash with biomimetic zinc-carbonate hydroxyapatite were shown to provide benefits according to the aims of this review.
METHODS: A literature search (Pubmed/MEDLINE and Scopus) of articles from 2003 to 2023 was conducted to analyze studies focused on the use of zinc-hydroxyapatite products. Duplicates were eliminated from the 5065 articles found, leaving 2076 articles. Of these, 30 articles were analyzed based on the use of products with zinc-carbonate hydroxyapatite in these studies.
RESULTS: 30 articles were included. Most of the studies showed benefits in terms of remineralization and prevention of enamel demineralization in terms of occlusion of the dentinal tubules and reduction of dentinal hypersensitivity.
CONCLUSIONS: Oral care products such as toothpaste and mouthwash with biomimetic zinc-carbonate hydroxyapatite were shown to provide benefits according to the aims of this review.
摘要：
开发了仿生碳酸锌羟基磷灰石技术，以实现模拟牙釉质和牙本质的天然羟基磷灰石的材料，并在粘附到这些生物组织的亲和力方面具有良好的活性。这种活性成分的化学和物理特性使羟基磷灰石本身与牙科羟基磷灰石特别相似，增强仿生羟基磷灰石与牙科羟基磷灰石之间的结合。这篇综述的目的是评估这项技术在牙釉质和牙本质的益处以及减少牙齿过敏方面的功效。
方法：对2003年至2023年的文章进行了文献检索（Pubmed/MEDLINE和Scopus），以分析专注于锌-羟基磷灰石产品使用的研究。从发现的5065篇文章中删除了重复，留下2076篇文章。其中,在这些研究中，根据使用碳酸锌羟基磷灰石的产品对30篇文章进行了分析。
结果：包括30篇文章。大多数研究表明，在牙本质小管闭塞和减少牙本质超敏反应方面，在再矿化和预防牙釉质脱矿方面具有益处。
结论：根据本综述的目的，口腔护理产品如牙膏和含仿生碳酸锌羟基磷灰石的漱口水被证明具有益处。
方法：对2003年至2023年的文章进行了文献检索（Pubmed/MEDLINE和Scopus），以分析专注于锌-羟基磷灰石产品使用的研究。
结果：包括30篇文章。
结论：根据本综述的目的，口腔护理产品如牙膏和含仿生碳酸锌羟基磷灰石的漱口水被证明具有益处。
