PDF(Pubmed)
Abstract：
The human monkeypox disease has mainly been described in Western and Central Africa. Since May 2022, the monkeypox virus has been spreading worldwide in a new epidemiological pattern, where cases result from person-to-person transmission, and develop clinically milder or less typical illness than during previous outbreaks in endemic areas. The newly-emerging monkeypox disease needs to be described over the long term, to improve cases definitions, to implement prompt control measures against epidemics, and to provide supportive care. Hence, we first conducted a review of historical and recent outbreaks to define the full clinical spectrum of the monkeypox disease and its course known so far. Then, we built a self-administrated questionnaire collecting daily symptoms of the monkeypox infection to follow cases and their contacts, even remotely. This tool will assist in the management of cases, the surveillance of contacts, and the conduct of clinical studies.
摘要：
人类猴痘疾病主要在西非和中非被描述。自2022年5月以来，猴痘病毒以一种新的流行病学模式在世界范围内传播。如果案件是由人与人之间的传播引起的，与以前在流行地区爆发的疾病相比，在临床上发展得更温和或不太典型的疾病。新出现的猴痘疾病需要长期描述，为了改进案例定义，实施及时的流行病控制措施，并提供支持性护理。因此，我们首先对历史和最近的疫情进行了回顾，以确定猴痘疾病的全部临床谱及其迄今已知的病程。然后，我们建立了一份自我管理的问卷，收集猴痘感染的日常症状，以跟踪病例及其接触者，甚至远程。这一工具将协助处理案件,对联系人的监视,以及临床研究的开展。
