Abstract：
OBJECTIVE: To report a case of Enterobacter cloacae (E. cloacae) keratitis in a patient who underwent corneal crosslinking (CXL) for progressive keratoconus.
METHODS: A 19-year-old female underwent CXL for keratoconus in her left eye. The patient neglected her post-procedure medications and missed the follow-up visit. Subsequently, she presented on day-10 post CXL with redness and pain in the treated eye. Clinical examination revealed a ring-shape infiltrate measuring 7.8 mm in diameter. Culture indicated the presence of E. cloacae. Treatment with gentamicin failed after the emergence of resistance. The patient was successfully treated with amikacin and moxifloxacin over several weeks.
CONCLUSIONS: Judicious antibiotic selection is crucial to limit the emergence of resistance in multidrug-resistant (MDR) pathogens. All patients need to be educated about their role in the management plan.
METHODS: A 19-year-old female underwent CXL for keratoconus in her left eye. The patient neglected her post-procedure medications and missed the follow-up visit. Subsequently, she presented on day-10 post CXL with redness and pain in the treated eye. Clinical examination revealed a ring-shape infiltrate measuring 7.8 mm in diameter. Culture indicated the presence of E. cloacae. Treatment with gentamicin failed after the emergence of resistance. The patient was successfully treated with amikacin and moxifloxacin over several weeks.
CONCLUSIONS: Judicious antibiotic selection is crucial to limit the emergence of resistance in multidrug-resistant (MDR) pathogens. All patients need to be educated about their role in the management plan.
摘要：
目的：报告一例阴沟肠杆菌（E.泄殖腔）角膜炎，该患者因进行性圆锥角膜接受角膜交联（CXL）。
方法：一名19岁女性因左眼圆锥角膜行CXL。患者忽略了她的术后药物治疗，错过了随访。随后，她在CXL后第10天出现红肿和疼痛。临床检查显示直径为7.8mm的环形渗透物。培养表明阴沟肠球菌的存在。出现耐药性后，庆大霉素治疗失败。患者在几周内成功使用阿米卡星和莫西沙星治疗。
结论：合理选择抗生素对于限制多药耐药（MDR）病原体耐药性的出现至关重要。所有患者都需要接受有关其在管理计划中的作用的教育。
方法：一名19岁女性因左眼圆锥角膜行CXL。
结论：合理选择抗生素对于限制多药耐药（MDR）病原体耐药性的出现至关重要。
