Abstract：
Studies on sexuality in patients with chronic obstructive pulmonary disease (COPD) are scarce and have yielded conflicting results. Our aim was to determine the prevalence of erectile dysfunction (ED) and associated factors in patients with COPD.
Articles with data on ED prevalence in patients diagnosed with COPD through spirometry were searched for in the PubMed, Embase, Cochrane Library, and Virtual Health Library databases from the year of their creation until January 31, 2021. The prevalence of ED was assessed with a weighted mean of the studies. A meta-analysis was performed using the Peto fixed-effect model to evaluate the association of COPD with ED.
Fifteen studies were ultimately included. The weighted prevalence of ED was 74.6%. A meta-analysis with four studies and 519 individuals showed an association of COPD with ED (estimated weighted odds ratio 2.89, 95% CI 1.93-4.32, p<0.001), with a non-negligible degree of heterogeneity (I2 57%). In the systematic review, age, smoking, degree of obstruction, oxygen saturation, and previous health status were associated with a higher prevalence of ED.
ED is common in patients with COPD and its prevalence is higher than in the general population.
Articles with data on ED prevalence in patients diagnosed with COPD through spirometry were searched for in the PubMed, Embase, Cochrane Library, and Virtual Health Library databases from the year of their creation until January 31, 2021. The prevalence of ED was assessed with a weighted mean of the studies. A meta-analysis was performed using the Peto fixed-effect model to evaluate the association of COPD with ED.
Fifteen studies were ultimately included. The weighted prevalence of ED was 74.6%. A meta-analysis with four studies and 519 individuals showed an association of COPD with ED (estimated weighted odds ratio 2.89, 95% CI 1.93-4.32, p<0.001), with a non-negligible degree of heterogeneity (I2 57%). In the systematic review, age, smoking, degree of obstruction, oxygen saturation, and previous health status were associated with a higher prevalence of ED.
ED is common in patients with COPD and its prevalence is higher than in the general population.
摘要：
背景：关于慢性阻塞性肺疾病（COPD）患者性行为的研究很少，并且产生了相互矛盾的结果。我们的目的是确定COPD患者勃起功能障碍（ED）的患病率和相关因素。
方法：在PubMed中搜索了通过肺活量测定诊断为COPD的患者ED患病率数据的文章，Embase,科克伦图书馆,和虚拟健康图书馆数据库从其创建的年份到2021年1月31日。用研究的加权平均值评估ED的患病率。使用Peto固定效应模型进行荟萃分析，以评估COPD与ED的相关性。
结果：最终纳入了15项研究。ED的加权患病率为74.6%。一项包含4项研究和519名个体的荟萃分析显示COPD与ED之间存在关联(估计加权比值比2.89,95%CI1.93-4.32,p<0.001),具有不可忽视的异质性(I257%)。在系统审查中，年龄,吸烟,阻塞程度,氧饱和度,和以前的健康状况与较高的ED患病率相关。
结论：ED在COPD患者中很常见，其患病率高于普通人群。
方法：在PubMed中搜索了通过肺活量测定诊断为COPD的患者ED患病率数据的文章，
结果：最终纳入了15项研究。
结论：ED在COPD患者中很常见，其患病率高于普通人群。
