PDF(Pubmed)
Abstract：
Antitumour treatments are evolving, including bacteria-mediated cancer therapy which is concurrently an ancient and cutting-edge approach. Salmonella typhimurium is a widely studied bacterial species that colonizes tumor tissues, showing oncolytic and immune system-regulating properties. It can be used as a delivery vector for genes and drugs, supporting conventional treatments that lack tumor-targeting abilities. This article summarizes recent evidence on the anticancer mechanisms of S. typhimurium alone and in combination with other anticancer treatments, suggesting that it may be a suitable approach to disease management.
摘要：
抗肿瘤治疗正在发展，包括细菌介导的癌症治疗，这同时是一种古老而前沿的方法。鼠伤寒沙门氏菌 是一种广泛研究的细菌物种，可定植在肿瘤组织中，显示溶瘤和免疫系统调节特性。它可以用作基因和药物的递送载体，支持缺乏肿瘤靶向能力的常规治疗。本文总结了S 抗癌机制的最新证据。typhimurium 单独和与其他抗癌治疗组合，这表明它可能是一种合适的疾病管理方法。。
