%0 Review %T Salmonella typhimurium may support cancer treatment: a review. %A Yang Z %A Zou L %A Yue B %A Hu M %J Acta Biochim Biophys Sin (Shanghai) %V 55 %N 3 %D Feb 2023 25 %M 36786073 %F 3.511 %R 10.3724/abbs.2023007 %X Antitumour treatments are evolving, including bacteria-mediated cancer therapy which is concurrently an ancient and cutting-edge approach. Salmonella typhimurium is a widely studied bacterial species that colonizes tumor tissues, showing oncolytic and immune system-regulating properties. It can be used as a delivery vector for genes and drugs, supporting conventional treatments that lack tumor-targeting abilities. This article summarizes recent evidence on the anticancer mechanisms of S. typhimurium alone and in combination with other anticancer treatments, suggesting that it may be a suitable approach to disease management.