关键词: adjuvant therapy adrenal tumor adrenocortical carcinoma malignant phaeochromocytoma spinal metastasis surgery

来  源:   DOI:10.3389/fonc.2023.1110045   PDF(Pubmed)

Abstract:
UNASSIGNED: Spinal metastasis of malignant adrenal tumor (SMMAT) is an extremely rare and poorly understood malignant tumor originating from the adrenal gland. The objective of this study is to elucidate the clinical characteristics and discuss surgical management and outcomes of SMMAT.
UNASSIGNED: Included in this study were six SMMAT patients who received surgical treatment in our center between February 2013 and May 2022. Their clinical data and outcomes were retrospectively analyzed to gain a better understanding of SMMAT. In addition, ten cases from the literature focusing on SMMAT were also reviewed.
UNASSIGNED: Surgery was performed successfully, and the associated symptoms were relieved significantly in all patients postoperatively. The mean follow-up duration was 26.2 (range 3-55) months. Two patients died of tumor recurrence 12 and 48 months after operation respectively. The other four patients were alive at the last follow-up.
UNASSIGNED: The prognosis of SMMAT is usually poor. Preoperative embolization and early surgical radical resection can offer satisfactory clinical outcomes. The patient\'s health status, preoperative neurological function, tumor location and the resection mode are potential prognostic factors of SMMAT.
摘要:
UNASSIGNED:恶性肾上腺肿瘤(SMMAT)的脊柱转移是一种极为罕见且鲜为人知的起源于肾上腺的恶性肿瘤。本研究的目的是阐明SMMAT的临床特征并讨论手术治疗和结果。
UNASSIGNED:本研究包括6名在2013年2月至2022年5月期间在我们中心接受手术治疗的SMMAT患者。回顾性分析他们的临床数据和结果,以更好地了解SMMAT。此外,还回顾了10例针对SMMAT的文献。
未经证实:手术成功,所有患者术后相关症状均明显缓解。平均随访时间为26.2(范围3-55)个月。2例患者分别于术后12个月和48个月因肿瘤复发死亡。其他四名患者在最后一次随访中还活着。
未经证实:SMMAT的预后通常较差。术前栓塞和早期手术根治性切除可提供满意的临床疗效。病人的健康状况,术前神经功能,肿瘤位置和切除方式是影响SMMAT预后的潜在因素。
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