关键词: Aneurysmal Bone cysts Jaw cysts

Mesh : Adolescent Young Adult Humans Adult Retrospective Studies Bone Cysts, Aneurysmal / diagnostic imaging Radiography Bone Transplantation

来  源:   DOI:10.1186/s12903-023-02741-5

Abstract:
The purpose of this retrospective study was to investigate and compare the clinical, radiographic, pathological, pathogenesis, and therapeutic features of simple bone cysts (SBCs) and aneurysmal bone cysts (ABCs) of the jaw.
35 patients with SBCs and 6 patients with ABCs who received treatment at the Department of Oral and Maxillofacial Surgery, Zhejiang University School of Medicine from 2017 to 2022 were followed up and reviewed retrospectively.
The study included 41 patients, accounting for 2.14% of all jaw pathologies, with 35 patients having SBCs and 6 patients having ABCs; their average ages were 26.63 ± 13.62 years and 17.83 ± 7.88 years, respectively. The prevalence of SBC and ABC did not differ significantly by sex. The mandible was the most vulnerable area to be involved. Only 5.71% (2/35) of patients with SBCs and 16.7% (1/6) of patients with ABCs reported histories of previous trauma in the same region of the pseudocysts. A total of 42.86% (15/35) of SBC cases and 66.67% (4/6) of ABC cases had malocclusions. The radiographic features of pseudocysts varied in shape, were associated with the root, and unilocular or multilocular. All patients had curettage with or without bone graft or substitute implantation, and recurrences did not occur in 94.29% (33/35) of SBC patients and 100% (6/6) of ABC patients after a mean follow-up time of 26.23 ± 15.47 months and 21.67 ± 19.75 months, respectively.
Pseudocysts, including SBCs and ABCs, are benign osteolytic lesions without an epithelial lining that occur occasionally in the jaw, mostly in adolescents and young adults, and their incidence did not significantly differ by sex. The most vulnerable site of involvement is the mandible, and they are generally not overtly aggressive. Trauma has a less significant role in pseudocysts, but minor trauma, such as malocclusion, has the potential to influence pseudocyst development. The clinical presentation of pseudocysts lacks specificity, and most patients are asymptomatic and found incidentally during radiographs. Dental panoramic radiographs and CBCT cannot accurately distinguish between SBC and ABC, and the final diagnosis depends on pathological diagnosis. Curettage combined with bone grafting is currently the best treatment for both, with a 5.71% (2/35) recurrence rate for SBC and no recurrence found for ABC.
摘要:
目的:这项回顾性研究的目的是调查和比较临床,射线照相,病态,发病机制,以及颌骨单纯性骨囊肿(SBC)和动脉瘤性骨囊肿(ABCs)的治疗特征。
方法:在口腔颌面外科接受治疗的35例SBCs和6例ABCs患者,对2017年至2022年浙江大学医学院进行回顾性随访。
结果:该研究包括41名患者,占所有颌骨病变的2.14%,35例患者患有SBCs,6例患者患有ABCs;他们的平均年龄为26.63±13.62岁和17.83±7.88岁,分别。SBC和ABC的患病率在性别之间没有显着差异。下颌骨是最脆弱的区域。只有5.71%(2/35)的SBC患者和16.7%(1/6)的ABC患者报告了在假囊肿同一区域的先前创伤史。共42.86%(15/35)的SBC病例和66.67%(4/6)的ABC病例发生错牙合。假性囊肿的影像学特征在形状上有所不同,与根相关联,和单眼或多房性。所有患者均进行刮宫术或不进行植骨或替代植入,平均随访时间为26.23±15.47个月和21.67±19.75个月后,94.29%(33/35)的SBC患者和100%(6/6)的ABC患者均未出现复发,分别。
结论:假性囊肿,包括SBC和ABC,是良性溶骨性病变,没有上皮衬里,偶尔发生在颌骨,主要是青少年和年轻人,且其发病率因性别而无显著差异。最脆弱的部位是下颌骨,他们通常没有明显的攻击性。创伤在假性囊肿中的作用不那么重要,但是轻微的创伤,比如错牙合,有可能影响假性囊肿的发展。假性囊肿的临床表现缺乏特异性,大多数患者无症状,在X光片上偶然发现。牙科全景X光片和CBCT不能准确区分SBC和ABC,最终的诊断取决于病理诊断。刮治结合植骨是目前两者的最佳治疗方法,SBC复发率为5.71%(2/35),ABC无复发。
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