Abstract：
Flexible bronchoscopes are increasingly being used in diagnostic and therapeutic medicine and have obviated the need for and risks associated with general anesthesia. Here the authors present the case of a 2-y-old girl who was diagnosed with isolated pulmonary Langerhans cell histiocytosis by histopathology; a lung biopsy sample was obtained using a cryoprobe via a flexible bronchoscope. The girl was brought in with complaints of loss of weight, appetite loss, and rapid breathing for the past 2 mo. Examination revealed hypoxia, tachypnea, clubbing with failure to thrive, and bilateral crepitations on auscultation. Imaging studies showed ground-glass opacities with multiple cystic lesions in both lungs. A preliminary diagnosis of LCH was made, and transbronchial cryobiopsy was done via a flexible bronchoscope. Histopathology confirmed the diagnosis with Cluster of differentiation 1a (CD1a) staining. A flexible bronchoscope can be a useful tool for obtaining lung biopsy samples using a cryoprobe in children.
摘要：
柔性支气管镜越来越多地用于诊断和治疗医学，并且消除了对全身麻醉的需求和与全身麻醉相关的风险。在这里，作者介绍了一个2岁女孩的病例，该女孩通过组织病理学被诊断为孤立的肺朗格汉斯细胞组织细胞增生症；通过柔性支气管镜使用冷冻探针获得肺活检样本。这个女孩被带进来抱怨减肥，食欲减退,过去2个月呼吸急促.检查显示缺氧,呼吸急促,未能茁壮成长的俱乐部，和听诊时的双侧尿路。影像学检查显示，双肺有毛玻璃混浊伴多发囊性病变。初步诊断为LCH,经支气管冷冻活检是通过柔性支气管镜进行的。组织病理学用分化簇1a(CD1a)染色证实诊断。柔性支气管镜可以是在儿童中使用冷冻探针获得肺活检样本的有用工具。
