Abstract:
A 3.5-year-old female cheetah (Acinonyx jubatus) died after a 10-day history of anorexia, regurgitation and diarrhoea despite symptomatic therapy. At gross post-mortem examination, the stomach was blood-filled with mucosal thickening and multifocal ulcerations. The intestinal mucosa was thickened and reddened, and the intestinal lumen was filled with dark red to black pasty content. Gastric histological lesions were compatible with gastritis due to Helicobacter infection, which was confirmed by polymerase chain reaction. Histology of the intestines revealed a severe necrotizing neutrophilic enterocolitis with abundant intralesional curved to spiral bacteria, corresponding to Campylobacter jejuni, which were subsequently isolated from both small and large intestinal contents. No other intestinal pathogens were detected despite thorough investigations. These findings suggest that C. jejuni may have played an aetiological role in the enterocolitis. Such an association has not been previously reported in non-domestic felids.
摘要:
一名3.5岁的雌性猎豹(Acinonyxjubatus)在有10天的厌食症病史后死亡,尽管有对症治疗,反流和腹泻。在大体验尸时,胃部充血,粘膜增厚和多灶性溃疡。肠粘膜增厚和变红,肠腔充满暗红色至黑色糊状内容物。胃组织学病变与螺杆菌感染引起的胃炎相容,聚合酶链反应证实了这一点。肠的组织学显示严重的坏死性中性粒细胞性小肠结肠炎,伴有大量的病灶内弯曲成螺旋细菌,对应于空肠弯曲菌,随后从小肠和大肠内容物中分离。尽管进行了彻底的调查,但未发现其他肠道病原体。这些发现表明空肠弯曲杆菌可能在小肠结肠炎中发挥了病因作用。这种关联以前从未在非家庭felids中报告过。