Abstract：
The introduction of pneumococcal conjugate vaccines (PCV) into the childhood vaccination programme has reduced invasive pneumococcal disease (IPD). Although anticipated from data elsewhere, surveillance in Ireland has confirmed reductions in IPD amongst those ⩾65 years of age due to a decline of PCV serotypes in this age group. Currently, direct protection against IPD in the elderly is focused on immunisation with the 23-valent pneumococcal polysaccharide vaccine (PPV23). However, immunity may not be as effective as with PCV and, furthermore, PPV23 uptake is poor in Ireland. Hence, consideration should be given to providing a PCV to this age group.
摘要：
将肺炎球菌结合疫苗（PCV）引入儿童疫苗接种计划已减少了侵袭性肺炎球菌疾病（IPD）。尽管从其他地方的数据中可以预见，爱尔兰的监测已证实，由于该年龄组PCV血清型的下降，在65岁的人群中，IPD的减少。目前,针对老年人IPD的直接保护集中在用23价肺炎球菌多糖疫苗(PPV23)免疫。然而,免疫可能不如PCV有效，此外，爱尔兰的PPV23摄取较差。因此，应考虑为该年龄组提供PCV。
