关键词: Pustular psoriasis of pregnancy case report generalized pustular psoriasis impetigo herpetiformis

Mesh : Humans Pregnancy Female Adult Impetigo / complications diagnosis pathology Dermatitis Herpetiformis / diagnosis Cesarean Section Psoriasis / diagnosis drug therapy Skin / pathology Skin Diseases, Vesiculobullous / pathology

来  源:   DOI:10.11604/pamj.2022.43.104.33237   PDF(Pubmed)

Abstract:
Pustular psoriasis of pregnancy (PPP) also known as impetigo herpetiformis is a well-described dermatosis of pregnancy characterized by the fatal progression of disease for both the mother and the foetus if left untreated. A 28-year-old G2P1L1 pregnant mother at 28 weeks of gestation, came to outpatient department (OPD) with complaints of scaly skin lesions all over her body along with fever, nausea and generalised weakness. On examination, there were erythematous scaly patches in the trunk, back, hands and legs accompanied by formation of pustules in the periphery of the lesions. Histopathological examination was consistent with pustular psoriasis. Patient was managed with prednisolone (40 mg/day which was later tapered). Serial antenatal visits and ultrasounds were done to monitor the health of the mother and foetal growth. Under the support of obstetrician, patient delivered a healthy female baby through caesarean section under general anaesthesia. Her lesions persisted in the postpartum period, which later started reducing gradually.
摘要:
妊娠脓疱性牛皮癣(PPP),也称为脓疱疮疱疹样,是一种描述良好的妊娠皮肤病,其特征在于,如果不及时治疗,母亲和胎儿的疾病都会发生致命的进展。一位28岁的G2P1L1怀孕的母亲在妊娠28周时,来到门诊部(OPD),抱怨她全身有鳞片状皮肤损伤,并发烧,恶心和全身无力。在检查中,躯干上有红斑鳞片,回来,手和腿伴有在病变周围形成脓疱。组织病理学检查与脓疱型银屑病一致。患者用泼尼松龙(40mg/天,随后逐渐减少)管理。进行了连续的产前检查和超声波检查,以监测母亲的健康和胎儿的生长。在产科医生的支持下,患者在全身麻醉下通过剖腹产分娩了健康的女性婴儿。她的病变在产后持续存在,后来开始逐渐减少。
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