PDF(Pubmed)
Abstract：
Sex dimorphism has been implicated in oral health differences and the pathogenesis of oral diseases, such as tooth agenesis, periodontal disease, dental caries, and tooth loss. Tooth agenesis (TA) is one of the most common developmental anomalies in humans, and its prevalence and patterns are different across ethnic groups. The aim of this study was to investigate the phenotypes and sex-associated patterns of nonsyndromic tooth agenesis (TA) in Thai dental patients.
One thousand ninety panoramic radiographs were examined. One hundred and one subjects (37 males, 64 females, 15-20 years-old) with nonsyndromic TA were evaluated. Differences in TA prevalence between groups were analyzed using the chi-square or Fisher exact test.
The TA prevalence, excluding third molars, was 9.3% and more frequently found in the mandible compared with the maxilla. The maxilla demonstrated a higher prevalence of first premolar agenesis than the mandible (P = 0.012), while the mandible had a higher prevalence of second premolar agenesis than the maxilla (P = 0.031). There were significantly more males missing one tooth than females, however, there were more females missing two or more teeth than males (P = 0.042). A missing maxillary left lateral incisor was significantly more frequent in males (P = 0.019), while a missing mandibular right lateral incisor was more frequent in females (P = 0.025). In females, the pattern of two mandibular lateral incisors agenesis was the most common and significantly present in females more than males (P = 0.015). In contrast, the pattern of one mandibular left lateral incisor agenesis was only observed in males and significantly found in males more than females (P = 0.047).
We demonstrate sex-associated differences in nonsyndromic tooth agenesis. The prevalence of single tooth agenesis was higher in males, while that of two or more teeth agenesis was higher in females. We found different patterns of lateral incisor agenesis between males and females.
One thousand ninety panoramic radiographs were examined. One hundred and one subjects (37 males, 64 females, 15-20 years-old) with nonsyndromic TA were evaluated. Differences in TA prevalence between groups were analyzed using the chi-square or Fisher exact test.
The TA prevalence, excluding third molars, was 9.3% and more frequently found in the mandible compared with the maxilla. The maxilla demonstrated a higher prevalence of first premolar agenesis than the mandible (P = 0.012), while the mandible had a higher prevalence of second premolar agenesis than the maxilla (P = 0.031). There were significantly more males missing one tooth than females, however, there were more females missing two or more teeth than males (P = 0.042). A missing maxillary left lateral incisor was significantly more frequent in males (P = 0.019), while a missing mandibular right lateral incisor was more frequent in females (P = 0.025). In females, the pattern of two mandibular lateral incisors agenesis was the most common and significantly present in females more than males (P = 0.015). In contrast, the pattern of one mandibular left lateral incisor agenesis was only observed in males and significantly found in males more than females (P = 0.047).
We demonstrate sex-associated differences in nonsyndromic tooth agenesis. The prevalence of single tooth agenesis was higher in males, while that of two or more teeth agenesis was higher in females. We found different patterns of lateral incisor agenesis between males and females.
摘要：
背景：性别二态性与口腔健康差异和口腔疾病的发病机理有关，比如牙齿发育不全，牙周病,龋齿,牙齿脱落。牙齿发育不全（TA）是人类最常见的发育异常之一，其流行程度和模式因种族而异。这项研究的目的是调查泰国牙科患者的非综合征性牙齿发育不全（TA）的表型和性别相关模式。
方法：检查了1000张全景X射线照片。一百一十一名受试者(37名男性，64名女性,15-20岁）与非综合征TA进行了评估。使用卡方或Fisher精确检验分析组间TA患病率的差异。
结果：TA患病率，不包括第三磨牙，与上颌骨相比，下颌骨为9.3％，并且在下颌骨中更常见。上颌骨表现出第一前磨牙发育不全的患病率高于下颌骨（P=0.012），而下颌骨第二前磨牙发育不全的患病率高于上颌骨（P=0.031）。缺一颗牙齿的男性明显多于女性，然而,缺失两颗或两颗以上牙齿的女性多于男性(P=0.042)。上颌左外切牙缺失在男性中明显更常见（P=0.019），而女性下颌右侧切牙缺失更为常见（P=0.025）。在女性中，两个下颌侧切牙发育不全的模式在女性中最常见，并且比男性更明显（P=0.015）。相比之下,仅在男性中观察到一次下颌左侧切牙发育不全的模式，并且在男性中发现的明显多于女性（P=0.047）。
结论：我们证明了非综合征性牙齿发育不全的性别差异。男性单齿发育不全的患病率较高，而两个或两个以上牙齿发育不全的女性更高。我们发现男性和女性之间的侧切牙发育不全模式不同。
方法：检查了1000张全景X射线照片。一百一十一名受试者(37名男性，64名女性,15-20岁）与非综合征TA进行了评估。使用卡方或Fisher精确检验分析组间TA患病率的差异。
结果：TA患病率，不包括第三磨牙，与上颌骨相比，下颌骨为9.3％，并且在下颌骨中更常见。上颌骨表现出第一前磨牙发育不全的患病率高于下颌骨（P=0.012），而下颌骨第二前磨牙发育不全的患病率高于上颌骨（P=0.031）。缺一颗牙齿的男性明显多于女性，然而,缺失两颗或两颗以上牙齿的女性多于男性(P=0.042)。上颌左外切牙缺失在男性中明显更常见（P=0.019），而女性下颌右侧切牙缺失更为常见（P=0.025）。在女性中，两个下颌侧切牙发育不全的模式在女性中最常见，并且比男性更明显（P=0.015）。相比之下,仅在男性中观察到一次下颌左侧切牙发育不全的模式，并且在男性中发现的明显多于女性（P=0.047）。
结论：我们证明了非综合征性牙齿发育不全的性别差异。男性单齿发育不全的患病率较高，而两个或两个以上牙齿发育不全的女性更高。我们发现男性和女性之间的侧切牙发育不全模式不同。
