关键词: AIC, Akaike Information Criterion APGD, anteroposterior globe diameter APLD, anteroposterior lens diameter CC, correlation coefficient CI, confidence intervals Eye biometry Fetus GA, gestational age GD, globe diameter GS, globe surface area LD, lens diameter LS, lens surface area Lens growth Lens shape MR imaging MR, Magnetic Resonance OLS, ordinary least square Ocular globe growth SD, standard deviation SNR, signal-to noise ratio T2W, T2 weighted US, ultrasound

来  源:   DOI:10.1016/j.heliyon.2023.e12885   PDF(Pubmed)

Abstract:
UNASSIGNED: To study the growth model, shape, and developmental relationship of lens and eyeball, we used two-dimensional Magnetic Resonance (MR) imaging to investigate gestationally age-related changes in the selected ocular parameters in vivo.
UNASSIGNED: We retrospectively reviewed the MR images from 126 fetuses ranging from 21 to 39 weeks\' gestation. Ocular parameters on MR imaging of transverse plane were measured including lens diameter (LD), anteroposterior lens diameter (APLD), lens surface area (LS), globe diameter (GD), anteroposterior globe diameter (APGD), globe surface area (GS). The growth model of each biometric against gestational age (GA), aspect ratio of lens and globe (LD/APLD and GD/APGD), and growing relationship between the ratio of lens and globe surface area (LS/GS) were studied by statistical analysis.
UNASSIGNED: The growth model of most biometry for gestational age is logarithmic, except for the diameter of the ocular globe (GD and APGD) showing a quadratic growth pattern. Our study showed that the lens was consistently larger in the transverse than the anteroposterior diameters during 21-39 weeks(P < 0.001). Besides, the ratio of surface area (LS/GS) was not significantly changing with GA(P = 0.4908), while the increase of LS was significantly accorded with that of GS(P < 0.001).
UNASSIGNED: The lens shape throughout fetal life may take part in the process, shape changing from vertical ellipsoid, spherical to transversal ellipsoid, based on the logarithmically increased ratio of lens transverse and anteroposterior diameters. In the meanwhile, the aspect ratio of eyeball in late fetal life may imply a gradually spherical shape during gestation. Nomogram data from this study may provide appropriate information about morphological changes in the fetal lens and the synchronous relationship between lens and eyeball.
摘要:
未经批准:为了研究生长模型,形状,晶状体和眼球的发育关系,我们使用二维磁共振(MR)成像来研究体内选定眼部参数的与年龄相关的变化.
UNASSIGNED:我们回顾性回顾了126例妊娠21至39周胎儿的MR图像。测量横向平面MR成像的眼部参数,包括晶状体直径(LD),前后晶状体直径(APLD),透镜表面积(LS),球形直径(GD),前后球直径(APGD),地球表面面积(GS)。每个生物特征与胎龄(GA)的生长模型,镜头和球体的纵横比(LD/APLD和GD/APGD),并通过统计分析研究了晶状体与眼球表面积之比(LS/GS)之间的增长关系。
UNASSIGNED:大多数胎龄生物特征的生长模型是对数的,除了眼球直径(GD和APGD)显示出二次生长模式。我们的研究表明,在21-39周内,晶状体的横向直径始终大于前后直径(P<0.001)。此外,表面积比(LS/GS)随GA变化不显著(P=0.4908),LS的增加与GS的增加显着一致(P<0.001)。
未经证实:整个胎儿生命中的晶状体形状可能参与该过程,形状从垂直椭圆体改变,球形到横向椭圆体,基于晶状体横向和前后直径的对数增加比率。同时,胎儿晚期的眼球长宽比可能意味着在妊娠期间逐渐呈球形。这项研究的列线图数据可以提供有关胎儿晶状体形态变化以及晶状体与眼球之间同步关系的适当信息。
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