Abstract：
UNASSIGNED: Cholangiocarcinoma, a primary malignancy of epithelial cells of the bile ducts, has been shown to have increasing incidence rates globally. Many of the current advances aim to improve the accuracy of differentiation between benign biliary strictures and cholangiocarcinoma, which include endoscopic techniques, devices, image processing, and the use of genomic sequencing in acquired specimens.
UNASSIGNED: In this review, the authors explore the historical timeline of changes leading to modern management of cholangiocarcinoma, with special emphasis on endoscopic modalities and novel therapeutic interventions. The authors also expand on the strengths and shortcomings of endoscopic diagnostics and techniques in biliary drainage and finally discuss potential areas to focus for future research and development.
UNASSIGNED: Despite the advances in diagnosis and management of cholangiocarcinoma, there remain multiple tasks that are still awaiting to be completed. Next-generation sequencing in the diagnosis of cholangiocarcinoma needs to be further tested, validated, and easily obtainable. Other innovative diagnostic modalities, such as the use of artificial intelligence in cholangioscopy, may provide an effective complementary modality to existing techniques. A consensus on biliary drainage needs to be defined and account for longevity and patient convenience.
UNASSIGNED: In this review, the authors explore the historical timeline of changes leading to modern management of cholangiocarcinoma, with special emphasis on endoscopic modalities and novel therapeutic interventions. The authors also expand on the strengths and shortcomings of endoscopic diagnostics and techniques in biliary drainage and finally discuss potential areas to focus for future research and development.
UNASSIGNED: Despite the advances in diagnosis and management of cholangiocarcinoma, there remain multiple tasks that are still awaiting to be completed. Next-generation sequencing in the diagnosis of cholangiocarcinoma needs to be further tested, validated, and easily obtainable. Other innovative diagnostic modalities, such as the use of artificial intelligence in cholangioscopy, may provide an effective complementary modality to existing techniques. A consensus on biliary drainage needs to be defined and account for longevity and patient convenience.
摘要：
未经批准：胆管癌，胆管上皮细胞的原发性恶性肿瘤，已被证明在全球范围内发病率不断上升。目前的许多进展旨在提高良性胆管狭窄和胆管癌之间的鉴别准确性。其中包括内窥镜技术，设备,图像处理,以及在采集的标本中使用基因组测序。
未经评估：在本次审查中，作者探索了导致胆管癌现代管理的变化的历史时间表，特别强调内窥镜模式和新的治疗干预措施。作者还扩展了内镜诊断和胆道引流技术的优缺点，最后讨论了未来研究和开发的潜在领域。
未经授权：尽管胆管癌的诊断和治疗取得了进展，仍有多项任务等待完成。下一代测序在胆管癌诊断中需要进一步测试，已验证，并且容易获得。其他创新的诊断方式，例如在胆道镜检查中使用人工智能，可以为现有技术提供有效的补充方式。需要对胆道引流达成共识，并考虑到寿命和患者便利性。
未经评估：在本次审查中，作者探索了导致胆管癌现代管理的变化的历史时间表，特别强调内窥镜模式和新的治疗干预措施。作者还扩展了内镜诊断和胆道引流技术的优缺点，最后讨论了未来研究和开发的潜在领域。
未经授权：尽管胆管癌的诊断和治疗取得了进展，仍有多项任务等待完成。下一代测序在胆管癌诊断中需要进一步测试，已验证，并且容易获得。其他创新的诊断方式，例如在胆道镜检查中使用人工智能，可以为现有技术提供有效的补充方式。需要对胆道引流达成共识，并考虑到寿命和患者便利性。
