Abstract：
Antibiotic resistance continues to evolve and spread beyond all boundaries, resulting in an increase in morbidity and mortality for non-curable infectious diseases. Due to the failure of conventional antimicrobial therapy and the lack of introduction of a novel class of antibiotics, novel strategies have recently emerged to combat these multidrug-resistant infectious microorganisms. In this review, we highlight the development of effective antibiotic combinations and of antibiotics with non-antibiotic activity-enhancing compounds to address the widespread emergence of antibiotic-resistant strains.
摘要：
抗生素耐药性继续发展并传播到所有边界之外，导致不可治愈的传染病的发病率和死亡率增加。由于常规抗菌治疗的失败和缺乏新型抗生素的引入，最近出现了新的策略来对抗这些多重耐药的传染性微生物。在这次审查中,我们强调了有效的抗生素组合和抗生素与非抗生素活性增强化合物的开发,以解决抗生素耐药菌株的广泛出现.
